node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALDOA | ALDOB | ENSP00000336927 | ENSP00000363988 | aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity) | aldolase B, fructose-bisphosphate | 0.829 |
ALDOA | ALDOC | ENSP00000336927 | ENSP00000226253 | aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity) | aldolase C, fructose-bisphosphate | 0.981 |
ALDOA | G6PC3 | ENSP00000336927 | ENSP00000269097 | aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity) | glucose 6 phosphatase, catalytic, 3; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. May form with the glucose-6-phosphate transporter (SLC37A4/G6PT) a ubiquitously expressed complex responsible for glucose production through glycogenolysis and gluconeogenesis. Probably required for normal neutrophil function | 0.824 |
ALDOA | GPI | ENSP00000336927 | ENSP00000405573 | aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity) | glucose-6-phosphate isomerase; Besides it’s role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons | 0.980 |
ALDOA | PGM1 | ENSP00000336927 | ENSP00000360124 | aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity) | phosphoglucomutase 1 | 0.930 |
ALDOA | PGM2 | ENSP00000336927 | ENSP00000371393 | aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity) | phosphoglucomutase 2; Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. May also catalyze the interconversion of glucose-1-phosphate and glucose-6-phosphate. Has low glucose 1,6-bisphosphate synthase activity | 0.828 |
ALDOA | TKT | ENSP00000336927 | ENSP00000405455 | aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity) | transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate | 0.958 |
ALDOB | ALDOA | ENSP00000363988 | ENSP00000336927 | aldolase B, fructose-bisphosphate | aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity) | 0.829 |
ALDOB | ALDOC | ENSP00000363988 | ENSP00000226253 | aldolase B, fructose-bisphosphate | aldolase C, fructose-bisphosphate | 0.805 |
ALDOB | G6PC3 | ENSP00000363988 | ENSP00000269097 | aldolase B, fructose-bisphosphate | glucose 6 phosphatase, catalytic, 3; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. May form with the glucose-6-phosphate transporter (SLC37A4/G6PT) a ubiquitously expressed complex responsible for glucose production through glycogenolysis and gluconeogenesis. Probably required for normal neutrophil function | 0.813 |
ALDOB | GPI | ENSP00000363988 | ENSP00000405573 | aldolase B, fructose-bisphosphate | glucose-6-phosphate isomerase; Besides it’s role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons | 0.980 |
ALDOB | LCT | ENSP00000363988 | ENSP00000264162 | aldolase B, fructose-bisphosphate | lactase; LPH splits lactose in the small intestine | 0.440 |
ALDOB | PGM1 | ENSP00000363988 | ENSP00000360124 | aldolase B, fructose-bisphosphate | phosphoglucomutase 1 | 0.911 |
ALDOB | PGM2 | ENSP00000363988 | ENSP00000371393 | aldolase B, fructose-bisphosphate | phosphoglucomutase 2; Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. May also catalyze the interconversion of glucose-1-phosphate and glucose-6-phosphate. Has low glucose 1,6-bisphosphate synthase activity | 0.816 |
ALDOB | TKT | ENSP00000363988 | ENSP00000405455 | aldolase B, fructose-bisphosphate | transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate | 0.964 |
ALDOC | ALDOA | ENSP00000226253 | ENSP00000336927 | aldolase C, fructose-bisphosphate | aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity) | 0.981 |
ALDOC | ALDOB | ENSP00000226253 | ENSP00000363988 | aldolase C, fructose-bisphosphate | aldolase B, fructose-bisphosphate | 0.805 |
ALDOC | G6PC3 | ENSP00000226253 | ENSP00000269097 | aldolase C, fructose-bisphosphate | glucose 6 phosphatase, catalytic, 3; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. May form with the glucose-6-phosphate transporter (SLC37A4/G6PT) a ubiquitously expressed complex responsible for glucose production through glycogenolysis and gluconeogenesis. Probably required for normal neutrophil function | 0.833 |
ALDOC | GPI | ENSP00000226253 | ENSP00000405573 | aldolase C, fructose-bisphosphate | glucose-6-phosphate isomerase; Besides it’s role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons | 0.982 |
ALDOC | PGM1 | ENSP00000226253 | ENSP00000360124 | aldolase C, fructose-bisphosphate | phosphoglucomutase 1 | 0.925 |