Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMMECR1L | RFX7 | ENSP00000272647 | ENSP00000397644 | AMMECR1-like | regulatory factor X, 7 | 0.738 |
AMMECR1L | RNF165 | ENSP00000272647 | ENSP00000269439 | AMMECR1-like | ring finger protein 165 | 0.797 |
AMMECR1L | UHRF2 | ENSP00000272647 | ENSP00000276893 | AMMECR1-like | ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle network. Through cooperative DNA and histone binding, may contribute to a tighter epigenetic control of gene expression in differentiated cells. Ubiquitinates cyclins, CCND1 and CCNE1, in an apparently phosphorylation-independent manner and induces G1 arrest. Also ubiquitinates PCNP leading to its degradation by the proteasome. Appears to contribute to tumorigenesis | 0.508 |
C18orf25 | RNF165 | ENSP00000282059 | ENSP00000269439 | chromosome 18 open reading frame 25 | ring finger protein 165 | 0.507 |
CCDC11 | RNF165 | ENSP00000381553 | ENSP00000269439 | coiled-coil domain containing 11 | ring finger protein 165 | 0.564 |
RFX7 | AMMECR1L | ENSP00000397644 | ENSP00000272647 | regulatory factor X, 7 | AMMECR1-like | 0.738 |
RFX7 | RNF165 | ENSP00000397644 | ENSP00000269439 | regulatory factor X, 7 | ring finger protein 165 | 0.725 |
RFX7 | UHRF2 | ENSP00000397644 | ENSP00000276893 | regulatory factor X, 7 | ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle network. Through cooperative DNA and histone binding, may contribute to a tighter epigenetic control of gene expression in differentiated cells. Ubiquitinates cyclins, CCND1 and CCNE1, in an apparently phosphorylation-independent manner and induces G1 arrest. Also ubiquitinates PCNP leading to its degradation by the proteasome. Appears to contribute to tumorigenesis | 0.497 |
RNF165 | AMMECR1L | ENSP00000269439 | ENSP00000272647 | ring finger protein 165 | AMMECR1-like | 0.797 |
RNF165 | C18orf25 | ENSP00000269439 | ENSP00000282059 | ring finger protein 165 | chromosome 18 open reading frame 25 | 0.507 |
RNF165 | CCDC11 | ENSP00000269439 | ENSP00000381553 | ring finger protein 165 | coiled-coil domain containing 11 | 0.564 |
RNF165 | RFX7 | ENSP00000269439 | ENSP00000397644 | ring finger protein 165 | regulatory factor X, 7 | 0.725 |
RNF165 | SKI | ENSP00000269439 | ENSP00000367797 | ring finger protein 165 | v-ski sarcoma viral oncogene homolog (avian); May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling | 0.564 |
RNF165 | SKIL | ENSP00000269439 | ENSP00000259119 | ring finger protein 165 | SKI-like oncogene; May have regulatory role in cell division or differentiation in response to extracellular signals | 0.564 |
RNF165 | SMAD6 | ENSP00000269439 | ENSP00000288840 | ring finger protein 165 | SMAD family member 6; Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions | 0.564 |
RNF165 | SMAD7 | ENSP00000269439 | ENSP00000262158 | ring finger protein 165 | SMAD family member 7; Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A- PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator ( [...] | 0.564 |
RNF165 | UHRF2 | ENSP00000269439 | ENSP00000276893 | ring finger protein 165 | ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle network. Through cooperative DNA and histone binding, may contribute to a tighter epigenetic control of gene expression in differentiated cells. Ubiquitinates cyclins, CCND1 and CCNE1, in an apparently phosphorylation-independent manner and induces G1 arrest. Also ubiquitinates PCNP leading to its degradation by the proteasome. Appears to contribute to tumorigenesis | 0.567 |
RNF165 | ZMIZ2 | ENSP00000269439 | ENSP00000311778 | ring finger protein 165 | zinc finger, MIZ-type containing 2 | 0.477 |
SKI | RNF165 | ENSP00000367797 | ENSP00000269439 | v-ski sarcoma viral oncogene homolog (avian); May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling | ring finger protein 165 | 0.564 |
SKI | SKIL | ENSP00000367797 | ENSP00000259119 | v-ski sarcoma viral oncogene homolog (avian); May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage. Functions as a repressor of TGF-beta signaling | SKI-like oncogene; May have regulatory role in cell division or differentiation in response to extracellular signals | 0.996 |
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