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STRINGSTRING
GRID2 GRID2 CBLN3 CBLN3 NRXN1 NRXN1 CBLN2 CBLN2 LRRTM2 LRRTM2 NRXN2 NRXN2 NRXN3 NRXN3
"CBLN2" - cerebellin 2 precursor in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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Edges represent protein-protein associations
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Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
CBLN2cerebellin 2 precursor; May play role in synaptogenesis induction (By similarity) (224 aa)    
Predicted Functional Partners:
CBLN3
cerebellin 3 precursor; May be involved in synaptic functions in the CNS (By similarity) (205 aa)
        score_image   score_image score_image 0.593
LRRTM2
leucine rich repeat transmembrane neuronal 2; Involved in the development and maintenance of excitatory synapse in the vertebrate nervous system. Regulates surface expression of AMPA receptors and instructs the development of functional glutamate release sites. Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B (By similarity) (516 aa)
            score_image   0.585
GRID2
glutamate receptor, ionotropic, delta 2; Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists (1007 aa)
            score_image   0.481
NRXN1
neurexin 1; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis (By similarity) (1547 aa)
            score_image   0.445
NRXN3
neurexin 3; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May play a role in angiogenesis (By similarity) (1061 aa)
            score_image   0.445
NRXN2
neurexin 2; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling (1712 aa)
            score_image   0.445
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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