PFKL protein (Homo sapiens) - STRING network view

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PFKL

phosphofructokinase, liver; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP (780 aa)

Predicted Functional Partners:

PFKM

0.999

GPI

0.996

HK1

0.989

ALDOC

0.989

ALDOB

0.988

ALDOA

0.988

HK2

0.987

PFKP

0.987

HK3

0.986

PKLR

0.975

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDOA	ALDOB	ENSP00000336927	ENSP00000363988	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	aldolase B, fructose-bisphosphate	0.829
ALDOA	ALDOC	ENSP00000336927	ENSP00000226253	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	aldolase C, fructose-bisphosphate	0.981
ALDOA	GPI	ENSP00000336927	ENSP00000405573	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	glucose-6-phosphate isomerase; Besides it’s role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons	0.980
ALDOA	HK1	ENSP00000336927	ENSP00000384774	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	hexokinase 1	0.927
ALDOA	HK2	ENSP00000336927	ENSP00000290573	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	hexokinase 2	0.926
ALDOA	HK3	ENSP00000336927	ENSP00000292432	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	hexokinase 3 (white cell)	0.929
ALDOA	PFKL	ENSP00000336927	ENSP00000269848	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	phosphofructokinase, liver; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP	0.988
ALDOA	PFKM	ENSP00000336927	ENSP00000345771	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	phosphofructokinase, muscle; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP	0.986
ALDOA	PFKP	ENSP00000336927	ENSP00000370517	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	phosphofructokinase, platelet; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP	0.988
ALDOA	PKLR	ENSP00000336927	ENSP00000339933	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	pyruvate kinase, liver and RBC; Plays a key role in glycolysis (By similarity)	0.926
ALDOB	ALDOA	ENSP00000363988	ENSP00000336927	aldolase B, fructose-bisphosphate	aldolase A, fructose-bisphosphate; Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity)	0.829
ALDOB	ALDOC	ENSP00000363988	ENSP00000226253	aldolase B, fructose-bisphosphate	aldolase C, fructose-bisphosphate	0.805
ALDOB	GPI	ENSP00000363988	ENSP00000405573	aldolase B, fructose-bisphosphate	glucose-6-phosphate isomerase; Besides it’s role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons	0.980
ALDOB	HK1	ENSP00000363988	ENSP00000384774	aldolase B, fructose-bisphosphate	hexokinase 1	0.927
ALDOB	HK2	ENSP00000363988	ENSP00000290573	aldolase B, fructose-bisphosphate	hexokinase 2	0.922
ALDOB	HK3	ENSP00000363988	ENSP00000292432	aldolase B, fructose-bisphosphate	hexokinase 3 (white cell)	0.938
ALDOB	PFKL	ENSP00000363988	ENSP00000269848	aldolase B, fructose-bisphosphate	phosphofructokinase, liver; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP	0.988
ALDOB	PFKM	ENSP00000363988	ENSP00000345771	aldolase B, fructose-bisphosphate	phosphofructokinase, muscle; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP	0.988
ALDOB	PFKP	ENSP00000363988	ENSP00000370517	aldolase B, fructose-bisphosphate	phosphofructokinase, platelet; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP	0.988
ALDOB	PKLR	ENSP00000363988	ENSP00000339933	aldolase B, fructose-bisphosphate	pyruvate kinase, liver and RBC; Plays a key role in glycolysis (By similarity)	0.939

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