node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CAPN10 | RNPEPL1 | ENSP00000375844 | ENSP00000270357 | calpain 10 | arginyl aminopeptidase (aminopeptidase B)-like 1 | 0.756 |
CHRND | EIF4E2 | ENSP00000258385 | ENSP00000258416 | cholinergic receptor, nicotinic, delta (muscle); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | eukaryotic translation initiation factor 4E family member 2; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures | 0.470 |
CHRND | RNPEPL1 | ENSP00000258385 | ENSP00000270357 | cholinergic receptor, nicotinic, delta (muscle); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | arginyl aminopeptidase (aminopeptidase B)-like 1 | 0.515 |
CHRNG | EIF4E2 | ENSP00000374145 | ENSP00000258416 | cholinergic receptor, nicotinic, gamma (muscle); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | eukaryotic translation initiation factor 4E family member 2; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures | 0.448 |
CHRNG | RNPEPL1 | ENSP00000374145 | ENSP00000270357 | cholinergic receptor, nicotinic, gamma (muscle); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | arginyl aminopeptidase (aminopeptidase B)-like 1 | 0.510 |
EIF4E2 | CHRND | ENSP00000258416 | ENSP00000258385 | eukaryotic translation initiation factor 4E family member 2; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures | cholinergic receptor, nicotinic, delta (muscle); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | 0.470 |
EIF4E2 | CHRNG | ENSP00000258416 | ENSP00000374145 | eukaryotic translation initiation factor 4E family member 2; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures | cholinergic receptor, nicotinic, gamma (muscle); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | 0.448 |
EIF4E2 | RNPEPL1 | ENSP00000258416 | ENSP00000270357 | eukaryotic translation initiation factor 4E family member 2; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures | arginyl aminopeptidase (aminopeptidase B)-like 1 | 0.548 |
EIF4E2 | UBC | ENSP00000258416 | ENSP00000344818 | eukaryotic translation initiation factor 4E family member 2; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures | ubiquitin C | 0.545 |
HTR3D | RNPEPL1 | ENSP00000371929 | ENSP00000270357 | 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel | arginyl aminopeptidase (aminopeptidase B)-like 1 | 0.503 |
IGFN1 | RNPEPL1 | ENSP00000334714 | ENSP00000270357 | immunoglobulin-like and fibronectin type III domain containing 1 | arginyl aminopeptidase (aminopeptidase B)-like 1 | 0.546 |
PFDN1 | RNPEPL1 | ENSP00000261813 | ENSP00000270357 | prefoldin subunit 1; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins | arginyl aminopeptidase (aminopeptidase B)-like 1 | 0.583 |
PFDN1 | UBC | ENSP00000261813 | ENSP00000344818 | prefoldin subunit 1; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins | ubiquitin C | 0.636 |
RNPEPL1 | CAPN10 | ENSP00000270357 | ENSP00000375844 | arginyl aminopeptidase (aminopeptidase B)-like 1 | calpain 10 | 0.756 |
RNPEPL1 | CHRND | ENSP00000270357 | ENSP00000258385 | arginyl aminopeptidase (aminopeptidase B)-like 1 | cholinergic receptor, nicotinic, delta (muscle); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | 0.515 |
RNPEPL1 | CHRNG | ENSP00000270357 | ENSP00000374145 | arginyl aminopeptidase (aminopeptidase B)-like 1 | cholinergic receptor, nicotinic, gamma (muscle); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane | 0.510 |
RNPEPL1 | EIF4E2 | ENSP00000270357 | ENSP00000258416 | arginyl aminopeptidase (aminopeptidase B)-like 1 | eukaryotic translation initiation factor 4E family member 2; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures | 0.548 |
RNPEPL1 | HTR3D | ENSP00000270357 | ENSP00000371929 | arginyl aminopeptidase (aminopeptidase B)-like 1 | 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel | 0.503 |
RNPEPL1 | IGFN1 | ENSP00000270357 | ENSP00000334714 | arginyl aminopeptidase (aminopeptidase B)-like 1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.546 |
RNPEPL1 | PFDN1 | ENSP00000270357 | ENSP00000261813 | arginyl aminopeptidase (aminopeptidase B)-like 1 | prefoldin subunit 1; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins | 0.583 |