IGLON5 protein (Homo sapiens) - STRING network view

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Score

IGLON5

IgLON family member 5 (336 aa)

Predicted Functional Partners:

OR10S1

0.720

PYDC2

0.634

IRGQ

0.515

MAP1LC3C

0.499

ZNF729

0.472

LCE2C

0.472

ARHGEF15

0.471

SPRR2G

0.414

RHBDL1

0.414

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF15	IGLON5	ENSP00000355026	ENSP00000270642	Rho guanine nucleotide exchange factor (GEF) 15; Specific GEF for RhoA activation. Does not activate RAC1 or CDC42. Regulates vascular smooth muscle contractility. Negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2	IgLON family member 5	0.471
ARHGEF15	OR10S1	ENSP00000355026	ENSP00000431914	Rho guanine nucleotide exchange factor (GEF) 15; Specific GEF for RhoA activation. Does not activate RAC1 or CDC42. Regulates vascular smooth muscle contractility. Negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2	olfactory receptor, family 10, subfamily S, member 1; Odorant receptor (Potential)	0.405
IGLON5	ARHGEF15	ENSP00000270642	ENSP00000355026	IgLON family member 5	Rho guanine nucleotide exchange factor (GEF) 15; Specific GEF for RhoA activation. Does not activate RAC1 or CDC42. Regulates vascular smooth muscle contractility. Negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2	0.471
IGLON5	IRGQ	ENSP00000270642	ENSP00000387535	IgLON family member 5	immunity-related GTPase family, Q	0.515
IGLON5	LCE2C	ENSP00000270642	ENSP00000357772	IgLON family member 5	late cornified envelope 2C; Precursors of the cornified envelope of the stratum	0.472
IGLON5	MAP1LC3C	ENSP00000270642	ENSP00000349785	IgLON family member 5	microtubule-associated protein 1 light chain 3 gamma; Probably involved in formation of autophagosomal vacuoles (autophagosomes) (By similarity)	0.499
IGLON5	OR10S1	ENSP00000270642	ENSP00000431914	IgLON family member 5	olfactory receptor, family 10, subfamily S, member 1; Odorant receptor (Potential)	0.720
IGLON5	PYDC2	ENSP00000270642	ENSP00000428325	IgLON family member 5	pyrin domain containing 2; Inhibits NF-kappa-B signaling distally by affecting the nuclear accumulation of RELA. Disrupts the interaction between PYCARD and NLRP3	0.634
IGLON5	RHBDL1	ENSP00000270642	ENSP00000219551	IgLON family member 5	rhomboid, veinlet-like 1 (Drosophila); May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors (By similarity)	0.414
IGLON5	SPRR2G	ENSP00000270642	ENSP00000357737	IgLON family member 5	small proline-rich protein 2G; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity)	0.414
IGLON5	ZNF729	ENSP00000270642	ENSP00000469582	IgLON family member 5	zinc finger protein 729; May be involved in transcriptional regulation	0.472
IRGQ	IGLON5	ENSP00000387535	ENSP00000270642	immunity-related GTPase family, Q	IgLON family member 5	0.515
IRGQ	LCE2C	ENSP00000387535	ENSP00000357772	immunity-related GTPase family, Q	late cornified envelope 2C; Precursors of the cornified envelope of the stratum	0.471
IRGQ	OR10S1	ENSP00000387535	ENSP00000431914	immunity-related GTPase family, Q	olfactory receptor, family 10, subfamily S, member 1; Odorant receptor (Potential)	0.480
IRGQ	SPRR2G	ENSP00000387535	ENSP00000357737	immunity-related GTPase family, Q	small proline-rich protein 2G; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity)	0.414
IRGQ	ZNF729	ENSP00000387535	ENSP00000469582	immunity-related GTPase family, Q	zinc finger protein 729; May be involved in transcriptional regulation	0.471
LCE2C	IGLON5	ENSP00000357772	ENSP00000270642	late cornified envelope 2C; Precursors of the cornified envelope of the stratum	IgLON family member 5	0.472
LCE2C	IRGQ	ENSP00000357772	ENSP00000387535	late cornified envelope 2C; Precursors of the cornified envelope of the stratum	immunity-related GTPase family, Q	0.471
LCE2C	OR10S1	ENSP00000357772	ENSP00000431914	late cornified envelope 2C; Precursors of the cornified envelope of the stratum	olfactory receptor, family 10, subfamily S, member 1; Odorant receptor (Potential)	0.407
LCE2C	SPRR2G	ENSP00000357772	ENSP00000357737	late cornified envelope 2C; Precursors of the cornified envelope of the stratum	small proline-rich protein 2G; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity)	0.568

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