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STRINGSTRING
PACRGL PACRGL KDELR3 KDELR3 RCN3 RCN3 MBD3 MBD3 PCSK6 PCSK6 UBC UBC PRUNE2 PRUNE2
"RCN3" - reticulocalbin 3, EF-hand calcium binding domain in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RCN3reticulocalbin 3, EF-hand calcium binding domain (328 aa)    
Predicted Functional Partners:
PACRGL
PARK2 co-regulated-like (221 aa)
        score_image       0.603
PCSK6
proprotein convertase subtilisin/kexin type 6 (968 aa)
        score_image       0.576
MBD3
methyl-CpG binding domain protein 3; Does not bind DNA by itself. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing (291 aa)
        score_image       0.499
UBC
ubiquitin C (685 aa)
        score_image       0.483
KDELR3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3; Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi. This receptor recognizes K-D-E-L (By similarity) (220 aa)
      score_image     score_image   0.457
PRUNE2
prune homolog 2 (Drosophila) (3088 aa)
        score_image       0.422
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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