node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALB | C1S | ENSP00000295897 | ENSP00000328173 | albumin | complement component 1, s subcomponent | 0.459 |
ALB | FCN3 | ENSP00000295897 | ENSP00000270879 | albumin | ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota | 0.439 |
ALB | FN1 | ENSP00000295897 | ENSP00000346839 | albumin | fibronectin 1 | 0.955 |
BTAF1 | FCN3 | ENSP00000265990 | ENSP00000270879 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae); Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box in an ATP-dependent manner | ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota | 0.545 |
BTAF1 | GOSR1 | ENSP00000265990 | ENSP00000225724 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae); Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box in an ATP-dependent manner | golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide- sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an impor [...] | 0.512 |
C1S | ALB | ENSP00000328173 | ENSP00000295897 | complement component 1, s subcomponent | albumin | 0.459 |
C1S | FCN3 | ENSP00000328173 | ENSP00000270879 | complement component 1, s subcomponent | ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota | 0.400 |
C1S | MBL2 | ENSP00000328173 | ENSP00000363079 | complement component 1, s subcomponent | mannose-binding lectin (protein C) 2, soluble; Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA | 0.445 |
FCN3 | ALB | ENSP00000270879 | ENSP00000295897 | ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota | albumin | 0.439 |
FCN3 | BTAF1 | ENSP00000270879 | ENSP00000265990 | ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae); Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box in an ATP-dependent manner | 0.545 |
FCN3 | C1S | ENSP00000270879 | ENSP00000328173 | ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota | complement component 1, s subcomponent | 0.400 |
FCN3 | FN1 | ENSP00000270879 | ENSP00000346839 | ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota | fibronectin 1 | 0.510 |
FCN3 | GOSR1 | ENSP00000270879 | ENSP00000225724 | ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota | golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide- sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an impor [...] | 0.519 |
FCN3 | MASP1 | ENSP00000270879 | ENSP00000296280 | ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) | 0.939 |
FCN3 | MASP2 | ENSP00000270879 | ENSP00000383690 | ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota | mannan-binding lectin serine peptidase 2 | 0.618 |
FCN3 | MBL2 | ENSP00000270879 | ENSP00000363079 | ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota | mannose-binding lectin (protein C) 2, soluble; Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA | 0.563 |
FCN3 | NEURL | ENSP00000270879 | ENSP00000358795 | ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota | neuralized homolog (Drosophila); May function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1, thereby regulating the Notch pathway (By similarity) | 0.560 |
FCN3 | NEURL1B | ENSP00000270879 | ENSP00000358815 | ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota | neuralized homolog 1B (Drosophila); E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands | 0.560 |
FN1 | ALB | ENSP00000346839 | ENSP00000295897 | fibronectin 1 | albumin | 0.955 |
FN1 | FCN3 | ENSP00000346839 | ENSP00000270879 | fibronectin 1 | ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota | 0.510 |