node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACHE | CHAT | ENSP00000303211 | ENSP00000337103 | acetylcholinesterase | choline O-acetyltransferase; Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses | 0.951 |
ACHE | SLC44A3 | ENSP00000303211 | ENSP00000271227 | acetylcholinesterase | solute carrier family 44, member 3 | 0.900 |
ALOX12B | SLC44A3 | ENSP00000315167 | ENSP00000271227 | arachidonate 12-lipoxygenase, 12R type; Converts arachidonic acid to 12R- hydroperoxyeicosatetraenoic acid (12R-HPETE) | solute carrier family 44, member 3 | 0.533 |
AQP11 | SLC44A3 | ENSP00000318770 | ENSP00000271227 | aquaporin 11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity) | solute carrier family 44, member 3 | 0.448 |
CHAT | ACHE | ENSP00000337103 | ENSP00000303211 | choline O-acetyltransferase; Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses | acetylcholinesterase | 0.951 |
CHAT | SLC44A3 | ENSP00000337103 | ENSP00000271227 | choline O-acetyltransferase; Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses | solute carrier family 44, member 3 | 0.900 |
ECSIT | SLC44A3 | ENSP00000270517 | ENSP00000271227 | ECSIT homolog (Drosophila); Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity) | solute carrier family 44, member 3 | 0.457 |
RABL3 | SLC44A3 | ENSP00000273375 | ENSP00000271227 | RAB, member of RAS oncogene family-like 3 | solute carrier family 44, member 3 | 0.521 |
RABL3 | UBC | ENSP00000273375 | ENSP00000344818 | RAB, member of RAS oncogene family-like 3 | ubiquitin C | 0.721 |
SH3BP5 | SLC44A3 | ENSP00000373301 | ENSP00000271227 | SH3-domain binding protein 5 (BTK-associated); Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death | solute carrier family 44, member 3 | 0.559 |
SH3BP5 | UBC | ENSP00000373301 | ENSP00000344818 | SH3-domain binding protein 5 (BTK-associated); Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death | ubiquitin C | 0.632 |
SLC39A14 | SLC44A3 | ENSP00000289952 | ENSP00000271227 | solute carrier family 39 (zinc transporter), member 14; May mediate cellular uptake of nontransferrin-bound iron (By similarity). Broad-scope metal ion transporter with a preference for zinc uptake | solute carrier family 44, member 3 | 0.419 |
SLC39A14 | UBC | ENSP00000289952 | ENSP00000344818 | solute carrier family 39 (zinc transporter), member 14; May mediate cellular uptake of nontransferrin-bound iron (By similarity). Broad-scope metal ion transporter with a preference for zinc uptake | ubiquitin C | 0.867 |
SLC44A3 | ACHE | ENSP00000271227 | ENSP00000303211 | solute carrier family 44, member 3 | acetylcholinesterase | 0.900 |
SLC44A3 | ALOX12B | ENSP00000271227 | ENSP00000315167 | solute carrier family 44, member 3 | arachidonate 12-lipoxygenase, 12R type; Converts arachidonic acid to 12R- hydroperoxyeicosatetraenoic acid (12R-HPETE) | 0.533 |
SLC44A3 | AQP11 | ENSP00000271227 | ENSP00000318770 | solute carrier family 44, member 3 | aquaporin 11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity) | 0.448 |
SLC44A3 | CHAT | ENSP00000271227 | ENSP00000337103 | solute carrier family 44, member 3 | choline O-acetyltransferase; Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses | 0.900 |
SLC44A3 | ECSIT | ENSP00000271227 | ENSP00000270517 | solute carrier family 44, member 3 | ECSIT homolog (Drosophila); Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity) | 0.457 |
SLC44A3 | RABL3 | ENSP00000271227 | ENSP00000273375 | solute carrier family 44, member 3 | RAB, member of RAS oncogene family-like 3 | 0.521 |
SLC44A3 | SH3BP5 | ENSP00000271227 | ENSP00000373301 | solute carrier family 44, member 3 | SH3-domain binding protein 5 (BTK-associated); Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death | 0.559 |