node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACHE | EIF2D | ENSP00000303211 | ENSP00000271764 | acetylcholinesterase | eukaryotic translation initiation factor 2D | 0.576 |
DENR | EIF2D | ENSP00000280557 | ENSP00000271764 | density-regulated protein; May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Plays a role in the modulation of the translational profile of a subset of cancer- related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1 | eukaryotic translation initiation factor 2D | 0.791 |
DENR | EIF5B | ENSP00000280557 | ENSP00000289371 | density-regulated protein; May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Plays a role in the modulation of the translational profile of a subset of cancer- related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1 | eukaryotic translation initiation factor 5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity) | 0.454 |
EIF2D | ACHE | ENSP00000271764 | ENSP00000303211 | eukaryotic translation initiation factor 2D | acetylcholinesterase | 0.576 |
EIF2D | DENR | ENSP00000271764 | ENSP00000280557 | eukaryotic translation initiation factor 2D | density-regulated protein; May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Plays a role in the modulation of the translational profile of a subset of cancer- related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1 | 0.791 |
EIF2D | EIF5B | ENSP00000271764 | ENSP00000289371 | eukaryotic translation initiation factor 2D | eukaryotic translation initiation factor 5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity) | 0.498 |
EIF2D | FTSJ2 | ENSP00000271764 | ENSP00000242257 | eukaryotic translation initiation factor 2D | FtsJ RNA methyltransferase homolog 2 (E. coli); Probable methyltransferase | 0.436 |
EIF2D | GNG7 | ENSP00000271764 | ENSP00000371594 | eukaryotic translation initiation factor 2D | guanine nucleotide binding protein (G protein), gamma 7; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striat [...] | 0.414 |
EIF2D | HEXB | ENSP00000271764 | ENSP00000261416 | eukaryotic translation initiation factor 2D | hexosaminidase B (beta polypeptide); Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues | 0.576 |
EIF2D | MAPKAPK2 | ENSP00000271764 | ENSP00000356070 | eukaryotic translation initiation factor 2D | mitogen-activated protein kinase-activated protein kinase 2 | 0.414 |
EIF2D | NIP7 | ENSP00000271764 | ENSP00000254940 | eukaryotic translation initiation factor 2D | nuclear import 7 homolog (S. cerevisiae); Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly | 0.420 |
EIF2D | NSUN6 | ENSP00000271764 | ENSP00000366519 | eukaryotic translation initiation factor 2D | NOP2/Sun domain family, member 6; May have S-adenosyl-L-methionine-dependent methyl- transferase activity (Potential) | 0.582 |
EIF5B | DENR | ENSP00000289371 | ENSP00000280557 | eukaryotic translation initiation factor 5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity) | density-regulated protein; May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Plays a role in the modulation of the translational profile of a subset of cancer- related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1 | 0.454 |
EIF5B | EIF2D | ENSP00000289371 | ENSP00000271764 | eukaryotic translation initiation factor 5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity) | eukaryotic translation initiation factor 2D | 0.498 |
EIF5B | FTSJ2 | ENSP00000289371 | ENSP00000242257 | eukaryotic translation initiation factor 5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity) | FtsJ RNA methyltransferase homolog 2 (E. coli); Probable methyltransferase | 0.459 |
FTSJ2 | EIF2D | ENSP00000242257 | ENSP00000271764 | FtsJ RNA methyltransferase homolog 2 (E. coli); Probable methyltransferase | eukaryotic translation initiation factor 2D | 0.436 |
FTSJ2 | EIF5B | ENSP00000242257 | ENSP00000289371 | FtsJ RNA methyltransferase homolog 2 (E. coli); Probable methyltransferase | eukaryotic translation initiation factor 5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity) | 0.459 |
FTSJ2 | NIP7 | ENSP00000242257 | ENSP00000254940 | FtsJ RNA methyltransferase homolog 2 (E. coli); Probable methyltransferase | nuclear import 7 homolog (S. cerevisiae); Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly | 0.680 |
FTSJ2 | NSUN6 | ENSP00000242257 | ENSP00000366519 | FtsJ RNA methyltransferase homolog 2 (E. coli); Probable methyltransferase | NOP2/Sun domain family, member 6; May have S-adenosyl-L-methionine-dependent methyl- transferase activity (Potential) | 0.529 |
GNG7 | EIF2D | ENSP00000371594 | ENSP00000271764 | guanine nucleotide binding protein (G protein), gamma 7; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striat [...] | eukaryotic translation initiation factor 2D | 0.414 |