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STRINGSTRING
CASC4 CASC4 PQLC3 PQLC3 THSD7B THSD7B FAM154A FAM154A PRAM1 PRAM1 ZNRF2 ZNRF2
"THSD7B" - thrombospondin, type I, domain containing 7B in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THSD7Bthrombospondin, type I, domain containing 7B (1609 aa)    
Predicted Functional Partners:
FAM154A
family with sequence similarity 154, member A (474 aa)
            score_image   0.623
PRAM1
PML-RARA regulated adaptor molecule 1; May be involved in myeloid differentiation. May be involved in integrin signaling in neutrophils. Binds to PtdIns(4)P (670 aa)
            score_image   0.579
PQLC3
PQ loop repeat containing 3 (202 aa)
            score_image   0.548
CASC4
cancer susceptibility candidate 4 (436 aa)
            score_image   0.513
ZNRF2
zinc and ring finger 2; May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates (242 aa)
            score_image   0.424
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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