KIAA1715 protein (Homo sapiens) - STRING network view

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protein of unknown 3D structure

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Score

KIAA1715

KIAA1715; May be involved in limb and central nervous system development (By similarity) (428 aa)

Predicted Functional Partners:

MTX2

0.868

HOXD1

0.754

EVX2

0.749

HOXD12

0.590

HOXA13

0.581

TBC1D29

0.561

HOXA11

0.538

HOXD11

0.534

CHMP1A

0.517

HOXD13

0.517

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHMP1A	KIAA1715	ENSP00000380998	ENSP00000272748	charged multivesicular body protein 1A; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the [...]	KIAA1715; May be involved in limb and central nervous system development (By similarity)	0.517
EVX2	KIAA1715	ENSP00000312385	ENSP00000272748	even-skipped homeobox 2	KIAA1715; May be involved in limb and central nervous system development (By similarity)	0.749
EVX2	MTX2	ENSP00000312385	ENSP00000249442	even-skipped homeobox 2	metaxin 2; Involved in transport of proteins into the mitochondrion	0.748
HOXA11	KIAA1715	ENSP00000006015	ENSP00000272748	homeobox A11; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis	KIAA1715; May be involved in limb and central nervous system development (By similarity)	0.538
HOXA13	KIAA1715	ENSP00000222753	ENSP00000272748	homeobox A13; Sequence-specific, AT-rich binding transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior- posterior axis	KIAA1715; May be involved in limb and central nervous system development (By similarity)	0.581
HOXD1	HOXD11	ENSP00000328598	ENSP00000249504	homeobox D1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures	homeobox D11; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis	0.750
HOXD1	KIAA1715	ENSP00000328598	ENSP00000272748	homeobox D1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures	KIAA1715; May be involved in limb and central nervous system development (By similarity)	0.754
HOXD1	MTX2	ENSP00000328598	ENSP00000249442	homeobox D1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures	metaxin 2; Involved in transport of proteins into the mitochondrion	0.475
HOXD11	HOXD1	ENSP00000249504	ENSP00000328598	homeobox D11; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis	homeobox D1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures	0.750
HOXD11	KIAA1715	ENSP00000249504	ENSP00000272748	homeobox D11; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis	KIAA1715; May be involved in limb and central nervous system development (By similarity)	0.534
HOXD12	KIAA1715	ENSP00000385586	ENSP00000272748	homeobox D12; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis	KIAA1715; May be involved in limb and central nervous system development (By similarity)	0.590
HOXD13	KIAA1715	ENSP00000376322	ENSP00000272748	homeobox D13; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis	KIAA1715; May be involved in limb and central nervous system development (By similarity)	0.517
KIAA1715	CHMP1A	ENSP00000272748	ENSP00000380998	KIAA1715; May be involved in limb and central nervous system development (By similarity)	charged multivesicular body protein 1A; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the [...]	0.517
KIAA1715	EVX2	ENSP00000272748	ENSP00000312385	KIAA1715; May be involved in limb and central nervous system development (By similarity)	even-skipped homeobox 2	0.749
KIAA1715	HOXA11	ENSP00000272748	ENSP00000006015	KIAA1715; May be involved in limb and central nervous system development (By similarity)	homeobox A11; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis	0.538
KIAA1715	HOXA13	ENSP00000272748	ENSP00000222753	KIAA1715; May be involved in limb and central nervous system development (By similarity)	homeobox A13; Sequence-specific, AT-rich binding transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior- posterior axis	0.581
KIAA1715	HOXD1	ENSP00000272748	ENSP00000328598	KIAA1715; May be involved in limb and central nervous system development (By similarity)	homeobox D1; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures	0.754
KIAA1715	HOXD11	ENSP00000272748	ENSP00000249504	KIAA1715; May be involved in limb and central nervous system development (By similarity)	homeobox D11; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis	0.534
KIAA1715	HOXD12	ENSP00000272748	ENSP00000385586	KIAA1715; May be involved in limb and central nervous system development (By similarity)	homeobox D12; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis	0.590
KIAA1715	HOXD13	ENSP00000272748	ENSP00000376322	KIAA1715; May be involved in limb and central nervous system development (By similarity)	homeobox D13; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis	0.517

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