ZNF167 protein (Homo sapiens) - STRING network view

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ZNF167

zinc finger protein 167; May be involved in transcriptional regulation (754 aa)

Predicted Functional Partners:

UBC

0.856

ZSCAN21

0.773

SCAND1

0.759

ZKSCAN4

0.719

YOD1

0.655

RANBP2

0.626

USP44

0.625

OTUD7A

0.609

ZNF446

0.572

TCEANC

0.570

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OTUD7A	UBC	ENSP00000305926	ENSP00000344818	OTU domain containing 7A; Has deubiquitinating activity that is directed towards ’Lys-48’ or ’Lys-63’-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin (By similarity)	ubiquitin C	0.665
OTUD7A	ZNF167	ENSP00000305926	ENSP00000273320	OTU domain containing 7A; Has deubiquitinating activity that is directed towards ’Lys-48’ or ’Lys-63’-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin (By similarity)	zinc finger protein 167; May be involved in transcriptional regulation	0.609
RANBP2	SCAND1	ENSP00000283195	ENSP00000301995	RAN binding protein 2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Could also have isomerase or chaperone activity and may bind RNA or DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at ’Lys-490’ which is essential for the proper assembly of PML-NB	SCAN domain containing 1; May regulate transcriptional activity	0.465
RANBP2	UBC	ENSP00000283195	ENSP00000344818	RAN binding protein 2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Could also have isomerase or chaperone activity and may bind RNA or DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at ’Lys-490’ which is essential for the proper assembly of PML-NB	ubiquitin C	0.992
RANBP2	ZKSCAN4	ENSP00000283195	ENSP00000366509	RAN binding protein 2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Could also have isomerase or chaperone activity and may bind RNA or DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at ’Lys-490’ which is essential for the proper assembly of PML-NB	zinc finger with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes	0.465
RANBP2	ZNF167	ENSP00000283195	ENSP00000273320	RAN binding protein 2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Could also have isomerase or chaperone activity and may bind RNA or DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at ’Lys-490’ which is essential for the proper assembly of PML-NB	zinc finger protein 167; May be involved in transcriptional regulation	0.626
RANBP2	ZNF446	ENSP00000283195	ENSP00000472802	RAN binding protein 2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Could also have isomerase or chaperone activity and may bind RNA or DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at ’Lys-490’ which is essential for the proper assembly of PML-NB	zinc finger protein 446; May be involved in transcriptional regulation	0.465
RANBP2	ZSCAN21	ENSP00000283195	ENSP00000292450	RAN binding protein 2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Could also have isomerase or chaperone activity and may bind RNA or DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at ’Lys-490’ which is essential for the proper assembly of PML-NB	zinc finger and SCAN domain containing 21; Strong transcriptional activator (By similarity)	0.465
SCAND1	RANBP2	ENSP00000301995	ENSP00000283195	SCAN domain containing 1; May regulate transcriptional activity	RAN binding protein 2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Could also have isomerase or chaperone activity and may bind RNA or DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at ’Lys-490’ which is essential for the proper assembly of PML-NB	0.465
SCAND1	UBC	ENSP00000301995	ENSP00000344818	SCAN domain containing 1; May regulate transcriptional activity	ubiquitin C	0.416
SCAND1	ZKSCAN4	ENSP00000301995	ENSP00000366509	SCAN domain containing 1; May regulate transcriptional activity	zinc finger with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes	0.742
SCAND1	ZNF167	ENSP00000301995	ENSP00000273320	SCAN domain containing 1; May regulate transcriptional activity	zinc finger protein 167; May be involved in transcriptional regulation	0.759
SCAND1	ZSCAN21	ENSP00000301995	ENSP00000292450	SCAN domain containing 1; May regulate transcriptional activity	zinc finger and SCAN domain containing 21; Strong transcriptional activator (By similarity)	0.605
TCEANC	ZNF167	ENSP00000313886	ENSP00000273320	transcription elongation factor A (SII) N-terminal and central domain containing	zinc finger protein 167; May be involved in transcriptional regulation	0.570
UBC	OTUD7A	ENSP00000344818	ENSP00000305926	ubiquitin C	OTU domain containing 7A; Has deubiquitinating activity that is directed towards ’Lys-48’ or ’Lys-63’-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin (By similarity)	0.665
UBC	RANBP2	ENSP00000344818	ENSP00000283195	ubiquitin C	RAN binding protein 2; E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Could also have isomerase or chaperone activity and may bind RNA or DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1. Sumoylates PML at ’Lys-490’ which is essential for the proper assembly of PML-NB	0.992
UBC	SCAND1	ENSP00000344818	ENSP00000301995	ubiquitin C	SCAN domain containing 1; May regulate transcriptional activity	0.416
UBC	USP44	ENSP00000344818	ENSP00000258499	ubiquitin C	ubiquitin specific peptidase 44; Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome (APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex (also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts as a neg [...]	0.657
UBC	YOD1	ENSP00000344818	ENSP00000326813	ubiquitin C	YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae); Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP’s axial channel. Mediates deubiquitination of both ’Lys-48’- and ’Lys-63’-linked [...]	0.993
UBC	ZNF167	ENSP00000344818	ENSP00000273320	ubiquitin C	zinc finger protein 167; May be involved in transcriptional regulation	0.856

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