Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
GAS7 GAS7 KIF5C KIF5C CGN CGN ACTB ACTB KIF3B KIF3B MYH15 MYH15 HSP90AA1 HSP90AA1 KIF3C KIF3C HSP90AB1 HSP90AB1 KIF5A KIF5A KIF5B KIF5B
"MYH15" - myosin, heavy chain 15 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYH15myosin, heavy chain 15; Muscle contraction (By similarity) (1946 aa)    
Predicted Functional Partners:
ACTB
actin, beta (375 aa)
      score_image score_image score_image score_image   0.928
CGN
cingulin; Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier (1203 aa)
          score_image     0.800
GAS7
growth arrest-specific 7; May play a role in promoting maturation and morphological differentiation of cerebellar neurons (476 aa)
        score_image   score_image   0.764
KIF5A
kinesin family member 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (By similarity) (1032 aa)
        score_image   score_image   0.749
KIF5C
kinesin family member 5C (957 aa)
        score_image   score_image   0.749
KIF3B
kinesin family member 3B; Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro (By similarity) (747 aa)
        score_image   score_image   0.749
KIF5B
kinesin family member 5B; Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes (By similarity) (963 aa)
        score_image   score_image   0.749
KIF3C
kinesin family member 3C; Microtubule-based anterograde translocator for membranous organelles (By similarity) (793 aa)
        score_image   score_image   0.749
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (854 aa)
        score_image   score_image   0.740
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (724 aa)
        score_image   score_image   0.740
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: medium (52%)