node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTB | GAS7 | ENSP00000349960 | ENSP00000407552 | actin, beta | growth arrest-specific 7; May play a role in promoting maturation and morphological differentiation of cerebellar neurons | 0.675 |
ACTB | HSP90AA1 | ENSP00000349960 | ENSP00000335153 | actin, beta | heat shock protein 90kDa alpha (cytosolic), class A member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function | 0.864 |
ACTB | HSP90AB1 | ENSP00000349960 | ENSP00000325875 | actin, beta | heat shock protein 90kDa alpha (cytosolic), class B member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function | 0.907 |
ACTB | MYH15 | ENSP00000349960 | ENSP00000273353 | actin, beta | myosin, heavy chain 15; Muscle contraction (By similarity) | 0.928 |
CGN | MYH15 | ENSP00000271636 | ENSP00000273353 | cingulin; Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier | myosin, heavy chain 15; Muscle contraction (By similarity) | 0.800 |
GAS7 | ACTB | ENSP00000407552 | ENSP00000349960 | growth arrest-specific 7; May play a role in promoting maturation and morphological differentiation of cerebellar neurons | actin, beta | 0.675 |
GAS7 | MYH15 | ENSP00000407552 | ENSP00000273353 | growth arrest-specific 7; May play a role in promoting maturation and morphological differentiation of cerebellar neurons | myosin, heavy chain 15; Muscle contraction (By similarity) | 0.764 |
HSP90AA1 | ACTB | ENSP00000335153 | ENSP00000349960 | heat shock protein 90kDa alpha (cytosolic), class A member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function | actin, beta | 0.864 |
HSP90AA1 | HSP90AB1 | ENSP00000335153 | ENSP00000325875 | heat shock protein 90kDa alpha (cytosolic), class A member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function | heat shock protein 90kDa alpha (cytosolic), class B member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function | 0.999 |
HSP90AA1 | MYH15 | ENSP00000335153 | ENSP00000273353 | heat shock protein 90kDa alpha (cytosolic), class A member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function | myosin, heavy chain 15; Muscle contraction (By similarity) | 0.740 |
HSP90AB1 | ACTB | ENSP00000325875 | ENSP00000349960 | heat shock protein 90kDa alpha (cytosolic), class B member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function | actin, beta | 0.907 |
HSP90AB1 | HSP90AA1 | ENSP00000325875 | ENSP00000335153 | heat shock protein 90kDa alpha (cytosolic), class B member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function | heat shock protein 90kDa alpha (cytosolic), class A member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function | 0.999 |
HSP90AB1 | MYH15 | ENSP00000325875 | ENSP00000273353 | heat shock protein 90kDa alpha (cytosolic), class B member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function | myosin, heavy chain 15; Muscle contraction (By similarity) | 0.740 |
KIF3B | KIF3C | ENSP00000364864 | ENSP00000264712 | kinesin family member 3B; Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro (By similarity) | kinesin family member 3C; Microtubule-based anterograde translocator for membranous organelles (By similarity) | 0.901 |
KIF3B | MYH15 | ENSP00000364864 | ENSP00000273353 | kinesin family member 3B; Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro (By similarity) | myosin, heavy chain 15; Muscle contraction (By similarity) | 0.749 |
KIF3C | KIF3B | ENSP00000264712 | ENSP00000364864 | kinesin family member 3C; Microtubule-based anterograde translocator for membranous organelles (By similarity) | kinesin family member 3B; Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro (By similarity) | 0.901 |
KIF3C | MYH15 | ENSP00000264712 | ENSP00000273353 | kinesin family member 3C; Microtubule-based anterograde translocator for membranous organelles (By similarity) | myosin, heavy chain 15; Muscle contraction (By similarity) | 0.749 |
KIF5A | KIF5B | ENSP00000408979 | ENSP00000307078 | kinesin family member 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (By similarity) | kinesin family member 5B; Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes (By similarity) | 0.630 |
KIF5A | MYH15 | ENSP00000408979 | ENSP00000273353 | kinesin family member 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (By similarity) | myosin, heavy chain 15; Muscle contraction (By similarity) | 0.749 |
KIF5B | KIF5A | ENSP00000307078 | ENSP00000408979 | kinesin family member 5B; Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes (By similarity) | kinesin family member 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (By similarity) | 0.630 |