node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABHD14A | ALAS1 | ENSP00000273596 | ENSP00000309259 | abhydrolase domain containing 14A; Possible role in granule neuron development (By similarity) | aminolevulinate, delta-, synthase 1 | 0.601 |
ABHD14A | ALAS2 | ENSP00000273596 | ENSP00000332369 | abhydrolase domain containing 14A; Possible role in granule neuron development (By similarity) | aminolevulinate, delta-, synthase 2 | 0.616 |
ABHD14A | BZW2 | ENSP00000273596 | ENSP00000258761 | abhydrolase domain containing 14A; Possible role in granule neuron development (By similarity) | basic leucine zipper and W2 domains 2; May be involved in neuronal differentiation (By similarity) | 0.544 |
ABHD14A | GCAT | ENSP00000273596 | ENSP00000371110 | abhydrolase domain containing 14A; Possible role in granule neuron development (By similarity) | glycine C-acetyltransferase | 0.601 |
ABHD14A | GINS3 | ENSP00000273596 | ENSP00000401018 | abhydrolase domain containing 14A; Possible role in granule neuron development (By similarity) | GINS complex subunit 3 (Psf3 homolog); The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single- stranded DNA | 0.538 |
ABHD14A | PFAS | ENSP00000273596 | ENSP00000313490 | abhydrolase domain containing 14A; Possible role in granule neuron development (By similarity) | phosphoribosylformylglycinamidine synthase | 0.551 |
ABHD14A | SPTLC1 | ENSP00000273596 | ENSP00000262554 | abhydrolase domain containing 14A; Possible role in granule neuron development (By similarity) | serine palmitoyltransferase, long chain base subunit 1; Serine palmitoyltransferase (SPT). The heterodimer formed with SPTLC2 or SPTLC3 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. The SPTLC1- SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isoz [...] | 0.601 |
ABHD14A | SPTLC2 | ENSP00000273596 | ENSP00000216484 | abhydrolase domain containing 14A; Possible role in granule neuron development (By similarity) | serine palmitoyltransferase, long chain base subunit 2; Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate | 0.601 |
ABHD14A | SPTLC3 | ENSP00000273596 | ENSP00000381968 | abhydrolase domain containing 14A; Possible role in granule neuron development (By similarity) | serine palmitoyltransferase, long chain base subunit 3; Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, while the SPTLC1-SPTLC3-SPTSSB has the ability to use a broader range of acyl-CoAs without apparent preference | 0.601 |
ABHD14A | ZIC1 | ENSP00000273596 | ENSP00000282928 | abhydrolase domain containing 14A; Possible role in granule neuron development (By similarity) | Zic family member 1; Acts as a transcriptional activator. Involved in neurogenesis. Plays important roles in the early stage of organogenesis of the CNS, as well as during dorsal spinal cord development and maturation of the cerebellum. Involved in the spatial distribution of mossy fiber (MF) neurons within the pontine gray nucleus (PGN). Plays a role in the regulation of MF axon pathway choice. Promotes MF migration towards ipsilaterally- located cerebellar territories. May have a role in shear flow mechanotransduction in osteocytes. Retains nuclear GLI1 and GLI3 in the cytoplasm. Bin [...] | 0.861 |
ALAS1 | ABHD14A | ENSP00000309259 | ENSP00000273596 | aminolevulinate, delta-, synthase 1 | abhydrolase domain containing 14A; Possible role in granule neuron development (By similarity) | 0.601 |
ALAS1 | ALAS2 | ENSP00000309259 | ENSP00000332369 | aminolevulinate, delta-, synthase 1 | aminolevulinate, delta-, synthase 2 | 0.807 |
ALAS1 | GCAT | ENSP00000309259 | ENSP00000371110 | aminolevulinate, delta-, synthase 1 | glycine C-acetyltransferase | 0.912 |
ALAS2 | ABHD14A | ENSP00000332369 | ENSP00000273596 | aminolevulinate, delta-, synthase 2 | abhydrolase domain containing 14A; Possible role in granule neuron development (By similarity) | 0.616 |
ALAS2 | ALAS1 | ENSP00000332369 | ENSP00000309259 | aminolevulinate, delta-, synthase 2 | aminolevulinate, delta-, synthase 1 | 0.807 |
ALAS2 | GCAT | ENSP00000332369 | ENSP00000371110 | aminolevulinate, delta-, synthase 2 | glycine C-acetyltransferase | 0.909 |
BZW2 | ABHD14A | ENSP00000258761 | ENSP00000273596 | basic leucine zipper and W2 domains 2; May be involved in neuronal differentiation (By similarity) | abhydrolase domain containing 14A; Possible role in granule neuron development (By similarity) | 0.544 |
BZW2 | GINS3 | ENSP00000258761 | ENSP00000401018 | basic leucine zipper and W2 domains 2; May be involved in neuronal differentiation (By similarity) | GINS complex subunit 3 (Psf3 homolog); The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single- stranded DNA | 0.540 |
BZW2 | PFAS | ENSP00000258761 | ENSP00000313490 | basic leucine zipper and W2 domains 2; May be involved in neuronal differentiation (By similarity) | phosphoribosylformylglycinamidine synthase | 0.518 |
GCAT | ABHD14A | ENSP00000371110 | ENSP00000273596 | glycine C-acetyltransferase | abhydrolase domain containing 14A; Possible role in granule neuron development (By similarity) | 0.601 |