Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
TMEM30C TMEM30C TMEM30B TMEM30B ATP7B ATP7B MON2 MON2 ATP10D ATP10D UBC UBC ATP7A ATP7A ENSG00000232856 ENSG00000232856 FLII FLII EEF1G EEF1G TMEM30A TMEM30A
"ATP10D" - ATPase, class V, type 10D in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATP10DATPase, class V, type 10D (1426 aa)    
Predicted Functional Partners:
FLII
flightless I homolog (Drosophila); May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling. Involved in early embryonic development (By similarity). May play a role in regulation of cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation (1269 aa)
      score_image         0.701
TMEM30C
transmembrane protein 30C (113 aa)
      score_image score_image   score_image   0.649
TMEM30B
transmembrane protein 30B (351 aa)
      score_image score_image   score_image   0.608
UBC
ubiquitin C (685 aa)
        score_image       0.575
TMEM30A
transmembrane protein 30A (361 aa)
      score_image score_image   score_image   0.575
ENSG00000232856
hsa-mir-3654 (206 aa)
      score_image score_image   score_image   0.516
EEF1G
eukaryotic translation elongation factor 1 gamma; Probably plays a role in anchoring the complex to other cellular components (437 aa)
      score_image score_image   score_image   0.516
MON2
MON2 homolog (S. cerevisiae); May be required for traffic between late Golgi and early endosomes (By similarity) (1717 aa)
        score_image   score_image   0.475
ATP7B
ATPase, Cu++ transporting, beta polypeptide; Involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile (1465 aa)
      score_image     score_image   0.448
ATP7A
ATPase, Cu++ transporting, alpha polypeptide; May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells (1500 aa)
      score_image     score_image   0.422
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: low (29%)