Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | SLC10A4 | solute carrier family 10 (sodium/bile acid cotransporter family), member 4 (437 aa) | ||||||||||||
Predicted Functional Partners:
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 | SLC10A7 | solute carrier family 10 (sodium/bile acid cotransporter family), member 7 (340 aa) |
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0.802 | ||||||||||
 | OSCP1 | organic solute carrier partner 1; May be involved in drug clearance in the placenta (379 aa) |
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0.621 | ||||||||||
 | OR2L2 | olfactory receptor, family 2, subfamily L, member 2; Odorant receptor (Potential) (312 aa) |
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0.499 | ||||||||||
 | SNX10 | sorting nexin 10; May be involved in several stages of intracellular trafficking (By similarity). May play a role in endosome homeostasis. Overexpression causes formation of huge vacuoles (201 aa) |
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0.489 | ||||||||||
 | UBC | ubiquitin C (685 aa) |
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0.483 | ||||||||||
 | TMEM237 | transmembrane protein 237 (408 aa) |
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0.472 | ||||||||||
 | LPPR5 | Lipid phosphate phosphatase-related protein type 5 (321 aa) |
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0.470 | ||||||||||
 | LPPR1 | Lipid phosphate phosphatase-related protein type 1 (325 aa) |
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0.457 | ||||||||||
 | SLC10A5 | solute carrier family 10 (sodium/bile acid cotransporter family), member 5 (438 aa) |
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0.437 | ||||||||
 | SLC10A3 | solute carrier family 10 (sodium/bile acid cotransporter family), member 3; The ubiquitous expression and the conservation of the sequence in distant animal species suggest that the gene codes for a protein with housekeeping functions (477 aa) |
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0.411 | ||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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