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STRINGSTRING
ST3GAL6 ST3GAL6 KIAA1430 KIAA1430 C7orf49 C7orf49 PPM1L PPM1L DZIP1L DZIP1L ROPN1L ROPN1L SLC37A3 SLC37A3 RSPH3 RSPH3 CABYR CABYR AKAP3 AKAP3 SPA17 SPA17
"ROPN1L" - rhophilin associated tail protein 1-like in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
ROPN1Lrhophilin associated tail protein 1-like (230 aa)    
Predicted Functional Partners:
AKAP3
A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction (853 aa)
        score_image   score_image   0.936
CABYR
calcium binding tyrosine-(Y)-phosphorylation regulated; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium (493 aa)
            score_image   0.864
SPA17
sperm autoantigenic protein 17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity) (151 aa)
            score_image   0.862
SLC37A3
solute carrier family 37 (glycerol-3-phosphate transporter), member 3 (494 aa)
            score_image   0.691
RSPH3
radial spoke 3 homolog (Chlamydomonas) (560 aa)
        score_image       0.613
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L; Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6 (360 aa)
            score_image   0.591
C7orf49
chromosome 7 open reading frame 49; May act as a regulator of proteasome (By similarity) (157 aa)
            score_image   0.562
KIAA1430
KIAA1430 (532 aa)
            score_image   0.485
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6; Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3- sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1 (331 aa)
            score_image   0.476
DZIP1L
DAZ interacting protein 1-like (767 aa)
            score_image   0.465
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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