UGT3A1 protein (Homo sapiens) - STRING network view

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UGT3A1

UDP glycosyltransferase 3 family, polypeptide A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity) (523 aa)

Predicted Functional Partners:

ACAD11

0.740

GHR

0.577

UBXN1

0.552

FAM222A

0.510

UAP1L1

0.507

SLC35A2

0.503

ACAD10

0.499

LRRC28

0.473

C1orf114

0.471

ZNF660

0.471

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAD10	GHR	ENSP00000389813	ENSP00000230882	acyl-CoA dehydrogenase family, member 10; Acyl-CoA dehydrogenase only active with R- and S-2- methyl-C15-CoA	growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity)	0.412
ACAD10	UGT3A1	ENSP00000389813	ENSP00000274278	acyl-CoA dehydrogenase family, member 10; Acyl-CoA dehydrogenase only active with R- and S-2- methyl-C15-CoA	UDP glycosyltransferase 3 family, polypeptide A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity)	0.499
ACAD11	GHR	ENSP00000264990	ENSP00000230882	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity)	0.577
ACAD11	UGT3A1	ENSP00000264990	ENSP00000274278	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	UDP glycosyltransferase 3 family, polypeptide A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity)	0.740
C1orf114	FAM222A	ENSP00000356779	ENSP00000351783	chromosome 1 open reading frame 114	family with sequence similarity 222, member A	0.658
C1orf114	UAP1L1	ENSP00000356779	ENSP00000386935	chromosome 1 open reading frame 114	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1	0.508
C1orf114	UGT3A1	ENSP00000356779	ENSP00000274278	chromosome 1 open reading frame 114	UDP glycosyltransferase 3 family, polypeptide A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity)	0.471
C1orf114	ZNF660	ENSP00000356779	ENSP00000324605	chromosome 1 open reading frame 114	zinc finger protein 660; May be involved in transcriptional regulation	0.583
FAM222A	C1orf114	ENSP00000351783	ENSP00000356779	family with sequence similarity 222, member A	chromosome 1 open reading frame 114	0.658
FAM222A	UAP1L1	ENSP00000351783	ENSP00000386935	family with sequence similarity 222, member A	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1	0.580
FAM222A	UGT3A1	ENSP00000351783	ENSP00000274278	family with sequence similarity 222, member A	UDP glycosyltransferase 3 family, polypeptide A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity)	0.510
FAM222A	ZNF660	ENSP00000351783	ENSP00000324605	family with sequence similarity 222, member A	zinc finger protein 660; May be involved in transcriptional regulation	0.658
GHR	ACAD10	ENSP00000230882	ENSP00000389813	growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity)	acyl-CoA dehydrogenase family, member 10; Acyl-CoA dehydrogenase only active with R- and S-2- methyl-C15-CoA	0.412
GHR	ACAD11	ENSP00000230882	ENSP00000264990	growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity)	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	0.577
GHR	UGT3A1	ENSP00000230882	ENSP00000274278	growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity)	UDP glycosyltransferase 3 family, polypeptide A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity)	0.577
LRRC28	UGT3A1	ENSP00000304923	ENSP00000274278	leucine rich repeat containing 28	UDP glycosyltransferase 3 family, polypeptide A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity)	0.473
SLC35A2	UBXN1	ENSP00000247138	ENSP00000294119	solute carrier family 35 (UDP-galactose transporter), member A2; Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function	UBX domain protein 1; Ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. Specifically binds ’Lys-6’-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol	0.609
SLC35A2	UGT3A1	ENSP00000247138	ENSP00000274278	solute carrier family 35 (UDP-galactose transporter), member A2; Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function	UDP glycosyltransferase 3 family, polypeptide A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity)	0.503
UAP1L1	C1orf114	ENSP00000386935	ENSP00000356779	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1	chromosome 1 open reading frame 114	0.508
UAP1L1	FAM222A	ENSP00000386935	ENSP00000351783	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1	family with sequence similarity 222, member A	0.580

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