node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CIRH1A | DDX27 | ENSP00000327179 | ENSP00000360828 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | 0.931 |
CIRH1A | NOC3L | ENSP00000327179 | ENSP00000360412 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | nucleolar complex associated 3 homolog (S. cerevisiae); May be required for adipogenesis (By similarity) | 0.751 |
CIRH1A | NOM1 | ENSP00000327179 | ENSP00000275820 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | nucleolar protein with MIF4G domain 1; Plays a role in targeting PPP1CA to the nucleolus | 0.854 |
CIRH1A | NOP2 | ENSP00000327179 | ENSP00000382392 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | NOP2 nucleolar protein homolog (yeast); May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase | 0.883 |
CIRH1A | RBM19 | ENSP00000327179 | ENSP00000261741 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | RNA binding motif protein 19; Plays a role in embryo pre-implantation development (By similarity) | 0.963 |
CIRH1A | TBL3 | ENSP00000327179 | ENSP00000454836 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | transducin (beta)-like 3 | 0.985 |
DDX27 | CIRH1A | ENSP00000360828 | ENSP00000327179 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | 0.931 |
DDX27 | NOC3L | ENSP00000360828 | ENSP00000360412 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | nucleolar complex associated 3 homolog (S. cerevisiae); May be required for adipogenesis (By similarity) | 0.986 |
DDX27 | NOM1 | ENSP00000360828 | ENSP00000275820 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | nucleolar protein with MIF4G domain 1; Plays a role in targeting PPP1CA to the nucleolus | 0.751 |
DDX27 | NOP2 | ENSP00000360828 | ENSP00000382392 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | NOP2 nucleolar protein homolog (yeast); May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation. May act as ribosomal RNA methyltransferase | 0.997 |
DDX27 | RBM19 | ENSP00000360828 | ENSP00000261741 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | RNA binding motif protein 19; Plays a role in embryo pre-implantation development (By similarity) | 0.904 |
DDX27 | TBL3 | ENSP00000360828 | ENSP00000454836 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | transducin (beta)-like 3 | 0.892 |
EIF4A2 | EIF4A3 | ENSP00000326381 | ENSP00000269349 | eukaryotic translation initiation factor 4A2; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5’-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon | eukaryotic translation initiation factor 4A3; ATP-dependent RNA helicase. Component of a splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC, that remains bound to spliced mRNAs throughout all stages of mRNA metabolism, functions to mark the position of the exon-exon junction [...] | 0.907 |
EIF4A2 | NOM1 | ENSP00000326381 | ENSP00000275820 | eukaryotic translation initiation factor 4A2; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5’-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon | nucleolar protein with MIF4G domain 1; Plays a role in targeting PPP1CA to the nucleolus | 0.936 |
EIF4A2 | PNMA3 | ENSP00000326381 | ENSP00000359286 | eukaryotic translation initiation factor 4A2; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5’-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon | paraneoplastic Ma antigen 3 | 0.743 |
EIF4A3 | EIF4A2 | ENSP00000269349 | ENSP00000326381 | eukaryotic translation initiation factor 4A3; ATP-dependent RNA helicase. Component of a splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC, that remains bound to spliced mRNAs throughout all stages of mRNA metabolism, functions to mark the position of the exon-exon junction [...] | eukaryotic translation initiation factor 4A2; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5’-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon | 0.907 |
EIF4A3 | NOM1 | ENSP00000269349 | ENSP00000275820 | eukaryotic translation initiation factor 4A3; ATP-dependent RNA helicase. Component of a splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC, that remains bound to spliced mRNAs throughout all stages of mRNA metabolism, functions to mark the position of the exon-exon junction [...] | nucleolar protein with MIF4G domain 1; Plays a role in targeting PPP1CA to the nucleolus | 0.808 |
EIF4A3 | PNMA3 | ENSP00000269349 | ENSP00000359286 | eukaryotic translation initiation factor 4A3; ATP-dependent RNA helicase. Component of a splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC, that remains bound to spliced mRNAs throughout all stages of mRNA metabolism, functions to mark the position of the exon-exon junction [...] | paraneoplastic Ma antigen 3 | 0.416 |
NOC3L | CIRH1A | ENSP00000360412 | ENSP00000327179 | nucleolar complex associated 3 homolog (S. cerevisiae); May be required for adipogenesis (By similarity) | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | 0.751 |
NOC3L | DDX27 | ENSP00000360412 | ENSP00000360828 | nucleolar complex associated 3 homolog (S. cerevisiae); May be required for adipogenesis (By similarity) | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 | 0.986 |