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STRINGSTRING
XKR9 XKR9 SMS SMS COIL COIL NDRG3 NDRG3 SMEK2 SMEK2 LACTB2 LACTB2 TXNL1 TXNL1 PALM2 PALM2 UBE2H UBE2H NUP210 NUP210 SSU72 SSU72
"LACTB2" - lactamase, beta 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
LACTB2lactamase, beta 2 (288 aa)    
Predicted Functional Partners:
UBE2H
ubiquitin-conjugating enzyme E2H; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes ’Lys- 11’- and ’Lys-48’-linked polyubiquitination. Capable, in vitro, to ubiquitinate histone H2A (183 aa)
        score_image       0.920
SMS
spermine synthase; Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM) (366 aa)
      score_image score_image       0.662
XKR9
XK, Kell blood group complex subunit-related family, member 9 (373 aa)
            score_image   0.655
NDRG3
NDRG family member 3 (375 aa)
        score_image       0.644
SMEK2
SMEK homolog 2, suppressor of mek1 (Dictyostelium); Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers (849 aa)
        score_image       0.644
PALM2
paralemmin 2 (411 aa)
        score_image       0.644
SSU72
SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae); Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination. Plays a role in pre-mRNA polyadenylation via its interaction with SYMPK (194 aa)
        score_image       0.644
NUP210
nucleoporin 210kDa; Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity (1887 aa)
        score_image   score_image   0.644
COIL
coilin; Is a component of the nuclear coiled bodies (CBS) which are involved in the function or assembly/disassembly of nucleoplasmic snRNPs. During mitosis, CBS disassemble, coinciding with a mitotic-specific phosphorylation of p80 coilin (576 aa)
        score_image       0.644
TXNL1
thioredoxin-like 1; Active thioredoxin with a redox potential of about -250 mV (289 aa)
        score_image       0.644
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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