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STRINGSTRING
CCDC88A CCDC88A CCDC93 CCDC93 GRIP1 GRIP1 SYBU SYBU KIF5C KIF5C TRAK2 TRAK2 BSN BSN KIF5B KIF5B TRAK1 TRAK1 STX1B STX1B KIF5A KIF5A
"SYBU" - syntabulin in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYBUsyntabulin (syntaxin-interacting) (663 aa)    
Predicted Functional Partners:
KIF5B
kinesin family member 5B; Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes (By similarity) (963 aa)
        score_image   score_image   0.987
STX1B
syntaxin 1B; Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm (By similarity) (288 aa)
            score_image   0.836
BSN
bassoon (presynaptic cytomatrix protein); Is thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act through binding to ERC2/CAST1. Essential in regulated neurotransmitter release from a subset of brain glutamatergic synapses. Involved in the formation of the retinal photoreceptor ribbon synapses (By similarity) (3926 aa)
            score_image   0.744
KIF5C
kinesin family member 5C (957 aa)
            score_image   0.717
CCDC93
coiled-coil domain containing 93 (631 aa)
            score_image   0.620
CCDC88A
coiled-coil domain containing 88A (1870 aa)
            score_image   0.610
GRIP1
glutamate receptor interacting protein 1; May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons (1076 aa)
            score_image   0.570
KIF5A
kinesin family member 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL) (By similarity) (1032 aa)
            score_image   0.570
TRAK1
trafficking protein, kinesin binding 1; Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors (953 aa)
            score_image   0.566
TRAK2
trafficking protein, kinesin binding 2; May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR (By similarity) (914 aa)
            score_image   0.563
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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