node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTN2 | LRP12 | ENSP00000355537 | ENSP00000276654 | actinin, alpha 2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein | low density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor | 0.573 |
ACTN2 | MYOT | ENSP00000355537 | ENSP00000239926 | actinin, alpha 2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein | myotilin; Component of a complex of multiple actin cross-linking proteins. Involved in the control of myofibril assembly and stability at the Z lines in muscle cells | 0.511 |
ACTN2 | UBC | ENSP00000355537 | ENSP00000344818 | actinin, alpha 2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein | ubiquitin C | 0.872 |
GNB2L1 | LRP12 | ENSP00000426909 | ENSP00000276654 | guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 | low density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor | 0.609 |
GNB2L1 | UBC | ENSP00000426909 | ENSP00000344818 | guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 | ubiquitin C | 0.998 |
LRP12 | ACTN2 | ENSP00000276654 | ENSP00000355537 | low density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor | actinin, alpha 2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein | 0.573 |
LRP12 | GNB2L1 | ENSP00000276654 | ENSP00000426909 | low density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor | guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 | 0.609 |
LRP12 | LRP5L | ENSP00000276654 | ENSP00000384291 | low density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor | low density lipoprotein receptor-related protein 5-like | 0.478 |
LRP12 | MYOT | ENSP00000276654 | ENSP00000239926 | low density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor | myotilin; Component of a complex of multiple actin cross-linking proteins. Involved in the control of myofibril assembly and stability at the Z lines in muscle cells | 0.573 |
LRP12 | NMRK2 | ENSP00000276654 | ENSP00000168977 | low density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor | nicotinamide riboside kinase 2; Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis | 0.573 |
LRP12 | OR1L1 | ENSP00000276654 | ENSP00000310773 | low density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor | olfactory receptor, family 1, subfamily L, member 1; Odorant receptor (Potential) | 0.407 |
LRP12 | OR8D2 | ENSP00000276654 | ENSP00000350022 | low density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor | olfactory receptor, family 8, subfamily D, member 2; Odorant receptor (Potential). May be involved in taste perception | 0.499 |
LRP12 | SNAPIN | ENSP00000276654 | ENSP00000357674 | low density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor | SNAP-associated protein; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. May modulate a step between vesicle priming, fusion [...] | 0.573 |
LRP12 | UBC | ENSP00000276654 | ENSP00000344818 | low density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor | ubiquitin C | 0.483 |
LRP12 | ZFYVE9 | ENSP00000276654 | ENSP00000287727 | low density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor | zinc finger, FYVE domain containing 9; Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization | 0.573 |
LRP5L | LRP12 | ENSP00000384291 | ENSP00000276654 | low density lipoprotein receptor-related protein 5-like | low density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor | 0.478 |
MYOT | ACTN2 | ENSP00000239926 | ENSP00000355537 | myotilin; Component of a complex of multiple actin cross-linking proteins. Involved in the control of myofibril assembly and stability at the Z lines in muscle cells | actinin, alpha 2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein | 0.511 |
MYOT | LRP12 | ENSP00000239926 | ENSP00000276654 | myotilin; Component of a complex of multiple actin cross-linking proteins. Involved in the control of myofibril assembly and stability at the Z lines in muscle cells | low density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor | 0.573 |
NMRK2 | LRP12 | ENSP00000168977 | ENSP00000276654 | nicotinamide riboside kinase 2; Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis | low density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor | 0.573 |
OR1L1 | LRP12 | ENSP00000310773 | ENSP00000276654 | olfactory receptor, family 1, subfamily L, member 1; Odorant receptor (Potential) | low density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor | 0.407 |