C8orf76 protein (Homo sapiens) - STRING network view

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Score

C8orf76

chromosome 8 open reading frame 76 (380 aa)

Predicted Functional Partners:

FAM91A1

0.565

SKA2

0.457

MRPS23

0.418

DCAF13

0.412

ZFAND1

0.406

PAMR1

0.405

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C8orf76	DCAF13	ENSP00000276704	ENSP00000297579	chromosome 8 open reading frame 76	DDB1 and CUL4 associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex	0.412
C8orf76	FAM91A1	ENSP00000276704	ENSP00000335082	chromosome 8 open reading frame 76	family with sequence similarity 91, member A1	0.565
C8orf76	MRPS23	ENSP00000276704	ENSP00000320184	chromosome 8 open reading frame 76	mitochondrial ribosomal protein S23	0.418
C8orf76	PAMR1	ENSP00000276704	ENSP00000278360	chromosome 8 open reading frame 76	peptidase domain containing associated with muscle regeneration 1; May play a role in regeneration of skeletal muscle (By similarity)	0.405
C8orf76	SKA2	ENSP00000276704	ENSP00000333433	chromosome 8 open reading frame 76	spindle and kinetochore associated complex subunit 2; Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubu [...]	0.457
C8orf76	ZFAND1	ENSP00000276704	ENSP00000220669	chromosome 8 open reading frame 76	zinc finger, AN1-type domain 1	0.406
DCAF13	C8orf76	ENSP00000297579	ENSP00000276704	DDB1 and CUL4 associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex	chromosome 8 open reading frame 76	0.412
DCAF13	FAM91A1	ENSP00000297579	ENSP00000335082	DDB1 and CUL4 associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex	family with sequence similarity 91, member A1	0.433
FAM91A1	C8orf76	ENSP00000335082	ENSP00000276704	family with sequence similarity 91, member A1	chromosome 8 open reading frame 76	0.565
FAM91A1	DCAF13	ENSP00000335082	ENSP00000297579	family with sequence similarity 91, member A1	DDB1 and CUL4 associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex	0.433
FAM91A1	MRPS23	ENSP00000335082	ENSP00000320184	family with sequence similarity 91, member A1	mitochondrial ribosomal protein S23	0.450
FAM91A1	SKA2	ENSP00000335082	ENSP00000333433	family with sequence similarity 91, member A1	spindle and kinetochore associated complex subunit 2; Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubu [...]	0.470
MRPS23	C8orf76	ENSP00000320184	ENSP00000276704	mitochondrial ribosomal protein S23	chromosome 8 open reading frame 76	0.418
MRPS23	FAM91A1	ENSP00000320184	ENSP00000335082	mitochondrial ribosomal protein S23	family with sequence similarity 91, member A1	0.450
PAMR1	C8orf76	ENSP00000278360	ENSP00000276704	peptidase domain containing associated with muscle regeneration 1; May play a role in regeneration of skeletal muscle (By similarity)	chromosome 8 open reading frame 76	0.405
SKA2	C8orf76	ENSP00000333433	ENSP00000276704	spindle and kinetochore associated complex subunit 2; Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubu [...]	chromosome 8 open reading frame 76	0.457
SKA2	FAM91A1	ENSP00000333433	ENSP00000335082	spindle and kinetochore associated complex subunit 2; Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubu [...]	family with sequence similarity 91, member A1	0.470
ZFAND1	C8orf76	ENSP00000220669	ENSP00000276704	zinc finger, AN1-type domain 1	chromosome 8 open reading frame 76	0.406

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