| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACTA1 | ENO1 | ENSP00000355645 | ENSP00000234590 | actin, alpha 1, skeletal muscle; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | enolase 1, (alpha) | 0.541 |
| ACTA1 | HSPA8 | ENSP00000355645 | ENSP00000227378 | actin, alpha 1, skeletal muscle; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | heat shock 70kDa protein 8; Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19- CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex | 0.505 |
| ACTA1 | MEF2A | ENSP00000355645 | ENSP00000346389 | actin, alpha 1, skeletal muscle; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | myocyte enhancer factor 2A | 0.460 |
| ACTA1 | ZNF16 | ENSP00000355645 | ENSP00000276816 | actin, alpha 1, skeletal muscle; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | zinc finger protein 16; May be involved in transcriptional regulation | 0.592 |
| COMMD5 | ZNF16 | ENSP00000304544 | ENSP00000276816 | COMM domain containing 5; Down-regulates activation of NF-kappa-B | zinc finger protein 16; May be involved in transcriptional regulation | 0.582 |
| ECD | ZNF16 | ENSP00000401566 | ENSP00000276816 | ecdysoneless homolog (Drosophila); Novel regulator of p53 stability and function. May also be a transcriptional activator required for the expression of glycolytic genes | zinc finger protein 16; May be involved in transcriptional regulation | 0.577 |
| ENO1 | ACTA1 | ENSP00000234590 | ENSP00000355645 | enolase 1, (alpha) | actin, alpha 1, skeletal muscle; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | 0.541 |
| ENO1 | HSPA8 | ENSP00000234590 | ENSP00000227378 | enolase 1, (alpha) | heat shock 70kDa protein 8; Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19- CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex | 0.676 |
| ENO1 | ZNF16 | ENSP00000234590 | ENSP00000276816 | enolase 1, (alpha) | zinc finger protein 16; May be involved in transcriptional regulation | 0.551 |
| EPB42 | ZNF16 | ENSP00000300215 | ENSP00000276816 | erythrocyte membrane protein band 4.2; Probably plays an important role in the regulation of erythrocyte shape and mechanical properties | zinc finger protein 16; May be involved in transcriptional regulation | 0.543 |
| HSPA8 | ACTA1 | ENSP00000227378 | ENSP00000355645 | heat shock 70kDa protein 8; Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19- CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex | actin, alpha 1, skeletal muscle; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | 0.505 |
| HSPA8 | ENO1 | ENSP00000227378 | ENSP00000234590 | heat shock 70kDa protein 8; Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19- CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex | enolase 1, (alpha) | 0.676 |
| HSPA8 | UBA52 | ENSP00000227378 | ENSP00000388107 | heat shock 70kDa protein 8; Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19- CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex | ubiquitin A-52 residue ribosomal protein fusion product 1 | 0.923 |
| HSPA8 | ZNF16 | ENSP00000227378 | ENSP00000276816 | heat shock 70kDa protein 8; Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19- CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex | zinc finger protein 16; May be involved in transcriptional regulation | 0.547 |
| MEF2A | ACTA1 | ENSP00000346389 | ENSP00000355645 | myocyte enhancer factor 2A | actin, alpha 1, skeletal muscle; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells | 0.460 |
| MEF2A | ZNF16 | ENSP00000346389 | ENSP00000276816 | myocyte enhancer factor 2A | zinc finger protein 16; May be involved in transcriptional regulation | 0.839 |
| NOX4 | ZNF16 | ENSP00000263317 | ENSP00000276816 | NADPH oxidase 4; Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 4 displa [...] | zinc finger protein 16; May be involved in transcriptional regulation | 0.750 |
| UBA52 | HSPA8 | ENSP00000388107 | ENSP00000227378 | ubiquitin A-52 residue ribosomal protein fusion product 1 | heat shock 70kDa protein 8; Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19- CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex | 0.923 |
| UBA52 | ZNF16 | ENSP00000388107 | ENSP00000276816 | ubiquitin A-52 residue ribosomal protein fusion product 1 | zinc finger protein 16; May be involved in transcriptional regulation | 0.555 |
| ZNF101 | ZNF16 | ENSP00000319716 | ENSP00000276816 | zinc finger protein 101; May be involved in transcriptional regulation | zinc finger protein 16; May be involved in transcriptional regulation | 0.577 |
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