node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C14orf1 | CYP51A1 | ENSP00000256319 | ENSP00000003100 | chromosome 14 open reading frame 1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.743 |
C14orf1 | LBR | ENSP00000256319 | ENSP00000272163 | chromosome 14 open reading frame 1 | lamin B receptor; Anchors the lamina and the heterochromatin to the inner nuclear membrane | 0.789 |
C14orf1 | MSMO1 | ENSP00000256319 | ENSP00000261507 | chromosome 14 open reading frame 1 | methylsterol monooxygenase 1 | 0.916 |
C14orf1 | NSDHL | ENSP00000256319 | ENSP00000359297 | chromosome 14 open reading frame 1 | NAD(P) dependent steroid dehydrogenase-like | 0.845 |
C14orf1 | SC5DL | ENSP00000256319 | ENSP00000264027 | chromosome 14 open reading frame 1 | sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like; Catalyzes a dehydrogenation to introduce C5-6 double bond into lathosterol | 0.889 |
C14orf1 | SIGMAR1 | ENSP00000256319 | ENSP00000277010 | chromosome 14 open reading frame 1 | sigma non-opioid intracellular receptor 1 | 0.953 |
C14orf1 | SQLE | ENSP00000256319 | ENSP00000265896 | chromosome 14 open reading frame 1 | squalene epoxidase; Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway | 0.547 |
C14orf1 | TM7SF2 | ENSP00000256319 | ENSP00000279263 | chromosome 14 open reading frame 1 | transmembrane 7 superfamily member 2; Involved in the conversion of lanosterol to cholesterol | 0.795 |
CYP51A1 | C14orf1 | ENSP00000003100 | ENSP00000256319 | cytochrome P450, family 51, subfamily A, polypeptide 1 | chromosome 14 open reading frame 1 | 0.743 |
CYP51A1 | LBR | ENSP00000003100 | ENSP00000272163 | cytochrome P450, family 51, subfamily A, polypeptide 1 | lamin B receptor; Anchors the lamina and the heterochromatin to the inner nuclear membrane | 0.992 |
CYP51A1 | MSMO1 | ENSP00000003100 | ENSP00000261507 | cytochrome P450, family 51, subfamily A, polypeptide 1 | methylsterol monooxygenase 1 | 0.997 |
CYP51A1 | NSDHL | ENSP00000003100 | ENSP00000359297 | cytochrome P450, family 51, subfamily A, polypeptide 1 | NAD(P) dependent steroid dehydrogenase-like | 0.941 |
CYP51A1 | SC5DL | ENSP00000003100 | ENSP00000264027 | cytochrome P450, family 51, subfamily A, polypeptide 1 | sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like; Catalyzes a dehydrogenation to introduce C5-6 double bond into lathosterol | 0.993 |
CYP51A1 | SIGMAR1 | ENSP00000003100 | ENSP00000277010 | cytochrome P450, family 51, subfamily A, polypeptide 1 | sigma non-opioid intracellular receptor 1 | 0.957 |
CYP51A1 | SQLE | ENSP00000003100 | ENSP00000265896 | cytochrome P450, family 51, subfamily A, polypeptide 1 | squalene epoxidase; Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway | 0.978 |
CYP51A1 | TM7SF2 | ENSP00000003100 | ENSP00000279263 | cytochrome P450, family 51, subfamily A, polypeptide 1 | transmembrane 7 superfamily member 2; Involved in the conversion of lanosterol to cholesterol | 0.994 |
CYP51A1 | UBC | ENSP00000003100 | ENSP00000344818 | cytochrome P450, family 51, subfamily A, polypeptide 1 | ubiquitin C | 0.986 |
KCNH6 | SIGMAR1 | ENSP00000463533 | ENSP00000277010 | potassium voltage-gated channel, subfamily H (eag-related), member 6; Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, rectifying current (By similarity). Channel properties may be modulated by cAMP and subunit assembly | sigma non-opioid intracellular receptor 1 | 0.862 |
LBR | C14orf1 | ENSP00000272163 | ENSP00000256319 | lamin B receptor; Anchors the lamina and the heterochromatin to the inner nuclear membrane | chromosome 14 open reading frame 1 | 0.789 |
LBR | CYP51A1 | ENSP00000272163 | ENSP00000003100 | lamin B receptor; Anchors the lamina and the heterochromatin to the inner nuclear membrane | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.992 |