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HMGCS2 HMGCS2 MVK MVK MVD MVD HMGCS1 HMGCS1 FDFT1 FDFT1 IDI1 IDI1 CYP51A1 CYP51A1 GGPS1 GGPS1 FDPS FDPS IDI2 IDI2 SQLE SQLE
"IDI2" - isopentenyl-diphosphate delta isomerase 2 in Homo sapiens
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protein of unknown 3D structure
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Predicted Interactions
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IDI2isopentenyl-diphosphate delta isomerase 2; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (227 aa)    
Predicted Functional Partners:
MVD
mevalonate (diphospho) decarboxylase; Performs the first committed step in the biosynthesis of isoprenes (400 aa)
score_image     score_image   score_image score_image   0.958
FDPS
farnesyl diphosphate synthase; Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (419 aa)
score_image     score_image   score_image score_image   0.954
GGPS1
geranylgeranyl diphosphate synthase 1; Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins (300 aa)
score_image         score_image score_image   0.941
IDI1
isopentenyl-diphosphate delta isomerase 1; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (284 aa)
    score_image     score_image score_image score_image 0.903
HMGCS2
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial); This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase (508 aa)
score_image     score_image     score_image   0.765
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble); This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase (520 aa)
score_image     score_image     score_image   0.720
SQLE
squalene epoxidase; Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway (574 aa)
      score_image     score_image   0.663
FDFT1
farnesyl-diphosphate farnesyltransferase 1 (417 aa)
score_image     score_image     score_image   0.654
CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1 (509 aa)
      score_image     score_image   0.648
MVK
mevalonate kinase; May be a regulatory site in cholesterol biosynthetic pathway (396 aa)
score_image     score_image     score_image   0.616
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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