GLUD1 protein (Homo sapiens) - STRING network view

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Score

GLUD1

glutamate dehydrogenase 1; May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity) (558 aa)

Predicted Functional Partners:

GLUL

0.985

UBC

0.976

GOT2

0.961

ALDH18A1

0.952

GLS

0.951

CS

0.948

IDH1

0.944

IDH2

0.944

MDH1

0.939

ALDH4A1

0.929

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH18A1	ALDH4A1	ENSP00000360268	ENSP00000290597	aldehyde dehydrogenase 18 family, member A1	aldehyde dehydrogenase 4 family, member A1	0.979
ALDH18A1	CS	ENSP00000360268	ENSP00000342056	aldehyde dehydrogenase 18 family, member A1	citrate synthase	0.709
ALDH18A1	GLUD1	ENSP00000360268	ENSP00000277865	aldehyde dehydrogenase 18 family, member A1	glutamate dehydrogenase 1; May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity)	0.952
ALDH18A1	GLUL	ENSP00000360268	ENSP00000307900	aldehyde dehydrogenase 18 family, member A1	glutamate-ammonia ligase; This enzyme has 2 functions- it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). Essential for proliferation of fetal skin fibroblasts	0.616
ALDH18A1	GOT2	ENSP00000360268	ENSP00000245206	aldehyde dehydrogenase 18 family, member A1	glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2); Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids	0.899
ALDH18A1	UBC	ENSP00000360268	ENSP00000344818	aldehyde dehydrogenase 18 family, member A1	ubiquitin C	0.952
ALDH4A1	ALDH18A1	ENSP00000290597	ENSP00000360268	aldehyde dehydrogenase 4 family, member A1	aldehyde dehydrogenase 18 family, member A1	0.979
ALDH4A1	GLS	ENSP00000290597	ENSP00000317379	aldehyde dehydrogenase 4 family, member A1	glutaminase; Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity	0.914
ALDH4A1	GLUD1	ENSP00000290597	ENSP00000277865	aldehyde dehydrogenase 4 family, member A1	glutamate dehydrogenase 1; May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity)	0.929
ALDH4A1	GLUL	ENSP00000290597	ENSP00000307900	aldehyde dehydrogenase 4 family, member A1	glutamate-ammonia ligase; This enzyme has 2 functions- it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). Essential for proliferation of fetal skin fibroblasts	0.945
ALDH4A1	GOT2	ENSP00000290597	ENSP00000245206	aldehyde dehydrogenase 4 family, member A1	glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2); Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids	0.925
ALDH4A1	UBC	ENSP00000290597	ENSP00000344818	aldehyde dehydrogenase 4 family, member A1	ubiquitin C	0.541
CS	ALDH18A1	ENSP00000342056	ENSP00000360268	citrate synthase	aldehyde dehydrogenase 18 family, member A1	0.709
CS	GLS	ENSP00000342056	ENSP00000317379	citrate synthase	glutaminase; Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity	0.499
CS	GLUD1	ENSP00000342056	ENSP00000277865	citrate synthase	glutamate dehydrogenase 1; May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity)	0.948
CS	GLUL	ENSP00000342056	ENSP00000307900	citrate synthase	glutamate-ammonia ligase; This enzyme has 2 functions- it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). Essential for proliferation of fetal skin fibroblasts	0.725
CS	GOT2	ENSP00000342056	ENSP00000245206	citrate synthase	glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2); Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids	0.940
CS	IDH1	ENSP00000342056	ENSP00000260985	citrate synthase	isocitrate dehydrogenase 1 (NADP+), soluble	0.890
CS	IDH2	ENSP00000342056	ENSP00000331897	citrate synthase	isocitrate dehydrogenase 2 (NADP+), mitochondrial; Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex	0.904
CS	MDH1	ENSP00000342056	ENSP00000438144	citrate synthase	malate dehydrogenase 1, NAD (soluble)	0.987

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