ITPRIP protein (Homo sapiens) - STRING network view

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ITPRIP

inositol 1,4,5-trisphosphate receptor interacting protein; Enhances Ca(2+)-mediated inhibition of inositol 1,4,5- triphosphate receptor (ITPR) Ca(2+) release (547 aa)

Predicted Functional Partners:

UBC

0.730

ITPR1

0.576

MAB21L3

0.502

KIF26B

0.483

MB21D2

0.449

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ITPR1	ITPRIP	ENSP00000306253	ENSP00000278071	inositol 1,4,5-trisphosphate receptor, type 1; Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity)	inositol 1,4,5-trisphosphate receptor interacting protein; Enhances Ca(2+)-mediated inhibition of inositol 1,4,5- triphosphate receptor (ITPR) Ca(2+) release	0.576
ITPR1	UBC	ENSP00000306253	ENSP00000344818	inositol 1,4,5-trisphosphate receptor, type 1; Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity)	ubiquitin C	0.902
ITPRIP	ITPR1	ENSP00000278071	ENSP00000306253	inositol 1,4,5-trisphosphate receptor interacting protein; Enhances Ca(2+)-mediated inhibition of inositol 1,4,5- triphosphate receptor (ITPR) Ca(2+) release	inositol 1,4,5-trisphosphate receptor, type 1; Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity)	0.576
ITPRIP	KIF26B	ENSP00000278071	ENSP00000385545	inositol 1,4,5-trisphosphate receptor interacting protein; Enhances Ca(2+)-mediated inhibition of inositol 1,4,5- triphosphate receptor (ITPR) Ca(2+) release	kinesin family member 26B; Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction (By similarity)	0.483
ITPRIP	MAB21L3	ENSP00000278071	ENSP00000358512	inositol 1,4,5-trisphosphate receptor interacting protein; Enhances Ca(2+)-mediated inhibition of inositol 1,4,5- triphosphate receptor (ITPR) Ca(2+) release	mab-21-like 3 (C. elegans)	0.502
ITPRIP	MB21D2	ENSP00000278071	ENSP00000376246	inositol 1,4,5-trisphosphate receptor interacting protein; Enhances Ca(2+)-mediated inhibition of inositol 1,4,5- triphosphate receptor (ITPR) Ca(2+) release	Mab-21 domain containing 2	0.449
ITPRIP	UBC	ENSP00000278071	ENSP00000344818	inositol 1,4,5-trisphosphate receptor interacting protein; Enhances Ca(2+)-mediated inhibition of inositol 1,4,5- triphosphate receptor (ITPR) Ca(2+) release	ubiquitin C	0.730
KIF26B	ITPRIP	ENSP00000385545	ENSP00000278071	kinesin family member 26B; Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction (By similarity)	inositol 1,4,5-trisphosphate receptor interacting protein; Enhances Ca(2+)-mediated inhibition of inositol 1,4,5- triphosphate receptor (ITPR) Ca(2+) release	0.483
KIF26B	UBC	ENSP00000385545	ENSP00000344818	kinesin family member 26B; Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction (By similarity)	ubiquitin C	0.615
MAB21L3	ITPRIP	ENSP00000358512	ENSP00000278071	mab-21-like 3 (C. elegans)	inositol 1,4,5-trisphosphate receptor interacting protein; Enhances Ca(2+)-mediated inhibition of inositol 1,4,5- triphosphate receptor (ITPR) Ca(2+) release	0.502
MAB21L3	MB21D2	ENSP00000358512	ENSP00000376246	mab-21-like 3 (C. elegans)	Mab-21 domain containing 2	0.614
MB21D2	ITPRIP	ENSP00000376246	ENSP00000278071	Mab-21 domain containing 2	inositol 1,4,5-trisphosphate receptor interacting protein; Enhances Ca(2+)-mediated inhibition of inositol 1,4,5- triphosphate receptor (ITPR) Ca(2+) release	0.449
MB21D2	MAB21L3	ENSP00000376246	ENSP00000358512	Mab-21 domain containing 2	mab-21-like 3 (C. elegans)	0.614
MB21D2	UBC	ENSP00000376246	ENSP00000344818	Mab-21 domain containing 2	ubiquitin C	0.483
UBC	ITPR1	ENSP00000344818	ENSP00000306253	ubiquitin C	inositol 1,4,5-trisphosphate receptor, type 1; Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity)	0.902
UBC	ITPRIP	ENSP00000344818	ENSP00000278071	ubiquitin C	inositol 1,4,5-trisphosphate receptor interacting protein; Enhances Ca(2+)-mediated inhibition of inositol 1,4,5- triphosphate receptor (ITPR) Ca(2+) release	0.730
UBC	KIF26B	ENSP00000344818	ENSP00000385545	ubiquitin C	kinesin family member 26B; Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction (By similarity)	0.615
UBC	MB21D2	ENSP00000344818	ENSP00000376246	ubiquitin C	Mab-21 domain containing 2	0.483

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