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CADM1 CADM1 LRRC4C LRRC4C BAALC BAALC TRAF6 TRAF6 LRRC4B LRRC4B ENSG00000259305 ENSG00000259305 PAMR1 PAMR1 TRIM33 TRIM33 SLC1A2 SLC1A2 EOGT EOGT C8orf76 C8orf76
"PAMR1" - peptidase domain containing associated with muscle regeneration 1 in Homo sapiens
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protein of unknown 3D structure
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Predicted Interactions
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PAMR1peptidase domain containing associated with muscle regeneration 1; May play a role in regeneration of skeletal muscle (By similarity) (737 aa)    
Predicted Functional Partners:
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2; Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium (574 aa)
            score_image   0.745
LRRC4C
leucine rich repeat containing 4C; May promote neurite outgrowth of developing thalamic neurons (640 aa)
            score_image   0.670
BAALC
brain and acute leukemia, cytoplasmic; May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A (By similarity) (145 aa)
            score_image   0.626
TRIM33
tripartite motif containing 33; Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed-16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as a [...] (1127 aa)
            score_image   0.584
ENSG00000259305
ZHX1-C8ORF76 readthrough (292 aa)
            score_image   0.582
EOGT
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase; Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N- acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like domains (By similarity) (443 aa)
            score_image   0.508
TRAF6
TNF receptor-associated factor 6, E3 ubiquitin protein ligase; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of ’Lys-63’-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF- kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Ad [...] (522 aa)
            score_image   0.493
LRRC4B
leucine rich repeat containing 4B; Synaptic adhesion protein. Regulates the formation of excitatory synapses. The trans-synaptic adhesion between LRRC4B and PTPRF regulates the formation of excitatory synapses in a bidirectional manner (By similarity) (713 aa)
            score_image   0.485
CADM1
cell adhesion molecule 1; Mediates homophilic cell-cell adhesion in a Ca(2+)- independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachme [...] (442 aa)
            score_image   0.462
C8orf76
chromosome 8 open reading frame 76 (380 aa)
            score_image   0.405
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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