SLC22A9 protein (Homo sapiens) - STRING network view

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Score

SLC22A9

solute carrier family 22 (organic anion transporter), member 9 (553 aa)

Predicted Functional Partners:

SLC9A3R1

0.924

PDZK1

0.889

SLC26A6

0.715

SLCO1A2

0.703

SLC17A1

0.682

ABCC4

0.674

SLCO1C1

0.634

SLC13A3

0.630

SLCO1B1

0.623

SLCO4A1

0.584

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCC4	SLC13A3	ENSP00000366084	ENSP00000279027	ATP-binding cassette, sub-family C (CFTR/MRP), member 4; May be an organic anion pump relevant to cellular detoxification	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	0.451
ABCC4	SLC17A1	ENSP00000366084	ENSP00000244527	ATP-binding cassette, sub-family C (CFTR/MRP), member 4; May be an organic anion pump relevant to cellular detoxification	solute carrier family 17 (sodium phosphate), member 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane	0.568
ABCC4	SLC22A9	ENSP00000366084	ENSP00000279178	ATP-binding cassette, sub-family C (CFTR/MRP), member 4; May be an organic anion pump relevant to cellular detoxification	solute carrier family 22 (organic anion transporter), member 9	0.674
ABCC4	SLC26A6	ENSP00000366084	ENSP00000378920	ATP-binding cassette, sub-family C (CFTR/MRP), member 4; May be an organic anion pump relevant to cellular detoxification	solute carrier family 26, member 6; Does not seem to be involved in anion transport	0.691
ABCC4	SLC9A3R1	ENSP00000366084	ENSP00000262613	ATP-binding cassette, sub-family C (CFTR/MRP), member 4; May be an organic anion pump relevant to cellular detoxification	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli ( [...]	0.850
ABCC4	SLCO1A2	ENSP00000366084	ENSP00000305974	ATP-binding cassette, sub-family C (CFTR/MRP), member 4; May be an organic anion pump relevant to cellular detoxification	solute carrier organic anion transporter family, member 1A2; Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids (By similarity). Selectively inhibited by the grapefruit juice component naringin	0.738
ABCC4	SLCO1B1	ENSP00000366084	ENSP00000256958	ATP-binding cassette, sub-family C (CFTR/MRP), member 4; May be an organic anion pump relevant to cellular detoxification	solute carrier organic anion transporter family, member 1B1; Mediates the Na(+)-independent uptake of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. Involved in the clearance of bile acids and organic anions from the liver	0.739
ABCC4	SLCO1C1	ENSP00000366084	ENSP00000370964	ATP-binding cassette, sub-family C (CFTR/MRP), member 4; May be an organic anion pump relevant to cellular detoxification	solute carrier organic anion transporter family, member 1C1; Mediates the Na(+)-independent high affinity transport of organic anions such as the thyroid hormones thyroxine (T4) and rT3. Other potential substrates, such as triiodothyronine (T3), 17-beta-glucuronosyl estradiol, estrone-3-sulfate and sulfobromophthalein (BSP) are transported with much lower efficiency. May play a signifiant role in regulating T4 flux into and out of the brain (By similarity)	0.588
ABCC4	SLCO4A1	ENSP00000366084	ENSP00000217159	ATP-binding cassette, sub-family C (CFTR/MRP), member 4; May be an organic anion pump relevant to cellular detoxification	solute carrier organic anion transporter family, member 4A1; Mediates the Na(+)-independent transport of organic anions such as the thyroid hormones T3 (triiodo-L-thyronine), T4 (thyroxine) and rT3, and of estrone-3-sulfate and taurocholate	0.542
PDZK1	SLC17A1	ENSP00000342143	ENSP00000244527	PDZ domain containing 1	solute carrier family 17 (sodium phosphate), member 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane	0.596
PDZK1	SLC22A9	ENSP00000342143	ENSP00000279178	PDZ domain containing 1	solute carrier family 22 (organic anion transporter), member 9	0.889
SLC13A3	ABCC4	ENSP00000279027	ENSP00000366084	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	ATP-binding cassette, sub-family C (CFTR/MRP), member 4; May be an organic anion pump relevant to cellular detoxification	0.451
SLC13A3	SLC17A1	ENSP00000279027	ENSP00000244527	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	solute carrier family 17 (sodium phosphate), member 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane	0.506
SLC13A3	SLC22A9	ENSP00000279027	ENSP00000279178	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	solute carrier family 22 (organic anion transporter), member 9	0.630
SLC13A3	SLC26A6	ENSP00000279027	ENSP00000378920	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	solute carrier family 26, member 6; Does not seem to be involved in anion transport	0.564
SLC13A3	SLCO1A2	ENSP00000279027	ENSP00000305974	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	solute carrier organic anion transporter family, member 1A2; Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids (By similarity). Selectively inhibited by the grapefruit juice component naringin	0.472
SLC13A3	SLCO1C1	ENSP00000279027	ENSP00000370964	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	solute carrier organic anion transporter family, member 1C1; Mediates the Na(+)-independent high affinity transport of organic anions such as the thyroid hormones thyroxine (T4) and rT3. Other potential substrates, such as triiodothyronine (T3), 17-beta-glucuronosyl estradiol, estrone-3-sulfate and sulfobromophthalein (BSP) are transported with much lower efficiency. May play a signifiant role in regulating T4 flux into and out of the brain (By similarity)	0.450
SLC17A1	ABCC4	ENSP00000244527	ENSP00000366084	solute carrier family 17 (sodium phosphate), member 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane	ATP-binding cassette, sub-family C (CFTR/MRP), member 4; May be an organic anion pump relevant to cellular detoxification	0.568
SLC17A1	PDZK1	ENSP00000244527	ENSP00000342143	solute carrier family 17 (sodium phosphate), member 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane	PDZ domain containing 1	0.596
SLC17A1	SLC13A3	ENSP00000244527	ENSP00000279027	solute carrier family 17 (sodium phosphate), member 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	0.506

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