| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANK2 | CNTN5 | ENSP00000349588 | ENSP00000279463 | ankyrin 2, neuronal; In skeletal muscle, required for proper localization of DMD and DCTN4 and for the formation and/or stability of a special subset of microtubules associated with costameres and neuromuscular junctions (By similarity). Attaches integral membrane proteins to cytoskeletal elements. Also binds to cytoskeletal proteins. Required for coordinate assembly of Na/Ca exchanger, Na/K ATPase and InsP3 receptor at sarcoplasmic reticulum sites in cardiomyocytes. Required for the coordinated expression of the Na/K ATPase, Na/Ca exchanger and beta-2-spectrin (SPTBN1) in the inner se [...] | contactin 5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity) | 0.743 |
| APLP1 | CNTN5 | ENSP00000221891 | ENSP00000279463 | amyloid beta (A4) precursor-like protein 1; May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I | contactin 5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity) | 0.918 |
| CD177 | CNTN5 | ENSP00000367248 | ENSP00000279463 | CD177 molecule | contactin 5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity) | 0.870 |
| CNTN5 | ANK2 | ENSP00000279463 | ENSP00000349588 | contactin 5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity) | ankyrin 2, neuronal; In skeletal muscle, required for proper localization of DMD and DCTN4 and for the formation and/or stability of a special subset of microtubules associated with costameres and neuromuscular junctions (By similarity). Attaches integral membrane proteins to cytoskeletal elements. Also binds to cytoskeletal proteins. Required for coordinate assembly of Na/Ca exchanger, Na/K ATPase and InsP3 receptor at sarcoplasmic reticulum sites in cardiomyocytes. Required for the coordinated expression of the Na/K ATPase, Na/Ca exchanger and beta-2-spectrin (SPTBN1) in the inner se [...] | 0.743 |
| CNTN5 | APLP1 | ENSP00000279463 | ENSP00000221891 | contactin 5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity) | amyloid beta (A4) precursor-like protein 1; May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I | 0.918 |
| CNTN5 | CD177 | ENSP00000279463 | ENSP00000367248 | contactin 5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity) | CD177 molecule | 0.870 |
| CNTN5 | CNTNAP2 | ENSP00000279463 | ENSP00000354778 | contactin 5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity) | contactin associated protein-like 2; May play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the juxtaparanodal region of the axo-glial junction | 0.779 |
| CNTN5 | CNTNAP3 | ENSP00000279463 | ENSP00000297668 | contactin 5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity) | contactin associated protein-like 3 | 0.752 |
| CNTN5 | CNTNAP3B | ENSP00000279463 | ENSP00000366787 | contactin 5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity) | contactin associated protein-like 3B | 0.776 |
| CNTN5 | CNTNAP4 | ENSP00000279463 | ENSP00000418741 | contactin 5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity) | contactin associated protein-like 4 | 0.952 |
| CNTN5 | CNTNAP5 | ENSP00000279463 | ENSP00000399013 | contactin 5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity) | contactin associated protein-like 5; May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication | 0.789 |
| CNTN5 | PRL | ENSP00000279463 | ENSP00000302150 | contactin 5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity) | prolactin; Prolactin acts primarily on the mammary gland by promoting lactation | 0.823 |
| CNTN5 | PRLR | ENSP00000279463 | ENSP00000371432 | contactin 5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity) | prolactin receptor | 0.816 |
| CNTNAP2 | CNTN5 | ENSP00000354778 | ENSP00000279463 | contactin associated protein-like 2; May play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the juxtaparanodal region of the axo-glial junction | contactin 5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity) | 0.779 |
| CNTNAP3 | CNTN5 | ENSP00000297668 | ENSP00000279463 | contactin associated protein-like 3 | contactin 5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity) | 0.752 |
| CNTNAP3B | CNTN5 | ENSP00000366787 | ENSP00000279463 | contactin associated protein-like 3B | contactin 5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity) | 0.776 |
| CNTNAP4 | CNTN5 | ENSP00000418741 | ENSP00000279463 | contactin associated protein-like 4 | contactin 5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity) | 0.952 |
| CNTNAP5 | CNTN5 | ENSP00000399013 | ENSP00000279463 | contactin associated protein-like 5; May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication | contactin 5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity) | 0.789 |
| PRL | CNTN5 | ENSP00000302150 | ENSP00000279463 | prolactin; Prolactin acts primarily on the mammary gland by promoting lactation | contactin 5; Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity in the cerebral cortical neurons but not in hippocampal neurons. Probably involved in neuronal activity in the auditory system (By similarity) | 0.823 |
| PRL | PRLR | ENSP00000302150 | ENSP00000371432 | prolactin; Prolactin acts primarily on the mammary gland by promoting lactation | prolactin receptor | 0.999 |
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