Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | FAM124A | family with sequence similarity 124A (582 aa) | ||||||||||||
Predicted Functional Partners:
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 | OXSR1 | oxidative-stress responsive 1; Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton (527 aa) |
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0.594 | ||||||||||
 | ZFP64 | zinc finger protein 64 homolog (mouse); May be involved in transcriptional regulation (681 aa) |
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0.587 | ||||||||||
 | DAGLB | diacylglycerol lipase, beta (672 aa) |
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0.558 | ||||||||||
 | DLEU7 | deleted in lymphocytic leukemia, 7 (160 aa) |
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0.555 | ||||||||||
 | C21orf58 | chromosome 21 open reading frame 58 (322 aa) |
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0.532 | ||||||||||
 | ZZZ3 | zinc finger, ZZ-type containing 3; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (903 aa) |
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0.520 | ||||||||||
 | KLHDC7A | kelch domain containing 7A (777 aa) |
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0.509 | ||||||||||
 | SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense (253 aa) |
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0.508 | ||||||||||
 | ERCC6L2 | excision repair cross-complementing rodent repair deficiency, complementation group 6-like 2 (712 aa) |
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0.499 | ||||||||||
 | SLC37A2 | solute carrier family 37 (glycerol-3-phosphate transporter), member 2 (505 aa) |
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0.473 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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