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STRINGSTRING
GPM6A GPM6A ILDR2 ILDR2 WDR17 WDR17 TTLL9 TTLL9 GADL1 GADL1 ZSCAN22 ZSCAN22 BTBD11 BTBD11
"WDR17" - WD repeat domain 17 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDR17WD repeat domain 17 (1322 aa)    
Predicted Functional Partners:
GPM6A
glycoprotein M6A; Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G- protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type [...] (278 aa)
            score_image   0.710
TTLL9
tubulin tyrosine ligase-like family, member 9; Probable tubulin polyglutamylase that forms polyglutamate side chains on tubulin. Probably acts when complexed with other proteins (By similarity) (439 aa)
            score_image   0.499
GADL1
glutamate decarboxylase-like 1 (521 aa)
            score_image   0.499
ZSCAN22
zinc finger and SCAN domain containing 22; May be involved in transcriptional regulation (491 aa)
            score_image   0.457
BTBD11
BTB (POZ) domain containing 11 (1104 aa)
            score_image   0.456
ILDR2
immunoglobulin-like domain containing receptor 2 (639 aa)
            score_image   0.413
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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