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STRINGSTRING
ROPN1B ROPN1B AKAP3 AKAP3 FSIP2 FSIP2 ROPN1 ROPN1 AKAP4 AKAP4 CES4A CES4A FSIP1 FSIP1 C15orf55 C15orf55 SP4 SP4 CBWD2 CBWD2 CACNG6 CACNG6
"FSIP1" - fibrous sheath interacting protein 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FSIP1fibrous sheath interacting protein 1 (581 aa)    
Predicted Functional Partners:
AKAP4
A kinase (PRKA) anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility (854 aa)
        score_image   score_image   0.812
CES4A
carboxylesterase 4A; Probable carboxylesterase (By similarity) (468 aa)
            score_image   0.747
SP4
Sp4 transcription factor; Binds to GT and GC boxes promoters elements. Probable transcriptional activator (784 aa)
            score_image   0.687
CACNG6
calcium channel, voltage-dependent, gamma subunit 6; Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity) (260 aa)
            score_image   0.623
C15orf55
chromosome 15 open reading frame 55 (1132 aa)
            score_image   0.600
FSIP2
fibrous sheath interacting protein 2 (6996 aa)
            score_image   0.597
AKAP3
A kinase (PRKA) anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction (853 aa)
            score_image   0.592
ROPN1B
rhophilin associated tail protein 1B (212 aa)
            score_image   0.584
ROPN1
rhophilin associated tail protein 1 (212 aa)
            score_image   0.584
CBWD2
COBW domain containing 2 (395 aa)
            score_image   0.564
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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