| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSG00000251357 | SLC2A13 | ENSP00000400325 | ENSP00000280871 | Uncharacterized protein | solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers | 0.515 |
| FAM190A | SLC2A13 | ENSP00000329482 | ENSP00000280871 | family with sequence similarity 190, member A | solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers | 0.532 |
| SLC22A1 | SLC2A13 | ENSP00000355930 | ENSP00000280871 | solute carrier family 22 (organic cation transporter), member 1; Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)- N-methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), coca [...] | solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers | 0.543 |
| SLC22A2 | SLC2A13 | ENSP00000355920 | ENSP00000280871 | solute carrier family 22 (organic cation transporter), member 2; Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited b [...] | solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers | 0.557 |
| SLC22A6 | SLC2A13 | ENSP00000367102 | ENSP00000280871 | solute carrier family 22 (organic anion transporter), member 6 | solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers | 0.476 |
| SLC2A13 | ENSG00000251357 | ENSP00000280871 | ENSP00000400325 | solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers | Uncharacterized protein | 0.515 |
| SLC2A13 | FAM190A | ENSP00000280871 | ENSP00000329482 | solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers | family with sequence similarity 190, member A | 0.532 |
| SLC2A13 | SLC22A1 | ENSP00000280871 | ENSP00000355930 | solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers | solute carrier family 22 (organic cation transporter), member 1; Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)- N-methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), coca [...] | 0.543 |
| SLC2A13 | SLC22A2 | ENSP00000280871 | ENSP00000355920 | solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers | solute carrier family 22 (organic cation transporter), member 2; Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited b [...] | 0.557 |
| SLC2A13 | SLC22A6 | ENSP00000280871 | ENSP00000367102 | solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers | solute carrier family 22 (organic anion transporter), member 6 | 0.476 |
| SLC2A13 | SLC5A11 | ENSP00000280871 | ENSP00000289932 | solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers | solute carrier family 5 (sodium/glucose cotransporter), member 11; Involved in the sodium-dependent cotransport of myo- inositol (MI) with a Na(+)-MI stoichiometry of 2-1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D- xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney | 0.607 |
| SLC2A13 | SLC5A3 | ENSP00000280871 | ENSP00000370543 | solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3; Prevents intracellular accumulation of high concentrations of myo-inositol (an osmolyte) that result in impairment of cellular function | 0.674 |
| SLC2A13 | SPIRE1 | ENSP00000280871 | ENSP00000387266 | solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers | spire homolog 1 (Drosophila); Acts as a actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis | 0.465 |
| SLC2A13 | UBB | ENSP00000280871 | ENSP00000304697 | solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers | ubiquitin B | 0.503 |
| SLC2A13 | UBC | ENSP00000280871 | ENSP00000344818 | solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers | ubiquitin C | 0.503 |
| SLC5A11 | SLC2A13 | ENSP00000289932 | ENSP00000280871 | solute carrier family 5 (sodium/glucose cotransporter), member 11; Involved in the sodium-dependent cotransport of myo- inositol (MI) with a Na(+)-MI stoichiometry of 2-1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D- xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney | solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers | 0.607 |
| SLC5A3 | SLC2A13 | ENSP00000370543 | ENSP00000280871 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3; Prevents intracellular accumulation of high concentrations of myo-inositol (an osmolyte) that result in impairment of cellular function | solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers | 0.674 |
| SLC5A3 | UBC | ENSP00000370543 | ENSP00000344818 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3; Prevents intracellular accumulation of high concentrations of myo-inositol (an osmolyte) that result in impairment of cellular function | ubiquitin C | 0.729 |
| SPIRE1 | SLC2A13 | ENSP00000387266 | ENSP00000280871 | spire homolog 1 (Drosophila); Acts as a actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis | solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers | 0.465 |
| UBB | SLC2A13 | ENSP00000304697 | ENSP00000280871 | ubiquitin B | solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers | 0.503 |
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