node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSG00000111780 | NARS2 | ENSP00000450281 | ENSP00000281038 | Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | 0.900 |
ENSG00000111780 | PET112 | ENSP00000450281 | ENSP00000263985 | Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial | PET112 homolog (yeast); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) | 0.800 |
ENSG00000111780 | QRSL1 | ENSP00000450281 | ENSP00000358042 | Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial | glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) | 0.800 |
EPRS | FARS2 | ENSP00000355890 | ENSP00000274680 | glutamyl-prolyl-tRNA synthetase | phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins | 0.891 |
EPRS | IARS2 | ENSP00000355890 | ENSP00000303279 | glutamyl-prolyl-tRNA synthetase | isoleucyl-tRNA synthetase 2, mitochondrial | 0.895 |
EPRS | MARS | ENSP00000355890 | ENSP00000262027 | glutamyl-prolyl-tRNA synthetase | methionyl-tRNA synthetase | 0.999 |
EPRS | MARS2 | ENSP00000355890 | ENSP00000282276 | glutamyl-prolyl-tRNA synthetase | methionyl-tRNA synthetase 2, mitochondrial | 0.986 |
EPRS | NARS2 | ENSP00000355890 | ENSP00000281038 | glutamyl-prolyl-tRNA synthetase | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | 0.794 |
EPRS | PET112 | ENSP00000355890 | ENSP00000263985 | glutamyl-prolyl-tRNA synthetase | PET112 homolog (yeast); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) | 0.675 |
EPRS | QRSL1 | ENSP00000355890 | ENSP00000358042 | glutamyl-prolyl-tRNA synthetase | glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) | 0.700 |
EPRS | RARS2 | ENSP00000355890 | ENSP00000358549 | glutamyl-prolyl-tRNA synthetase | arginyl-tRNA synthetase 2, mitochondrial | 0.913 |
EPRS | YARS | ENSP00000355890 | ENSP00000362576 | glutamyl-prolyl-tRNA synthetase | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) | 0.998 |
FARS2 | EPRS | ENSP00000274680 | ENSP00000355890 | phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins | glutamyl-prolyl-tRNA synthetase | 0.891 |
FARS2 | IARS2 | ENSP00000274680 | ENSP00000303279 | phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins | isoleucyl-tRNA synthetase 2, mitochondrial | 0.970 |
FARS2 | MARS | ENSP00000274680 | ENSP00000262027 | phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins | methionyl-tRNA synthetase | 0.947 |
FARS2 | MARS2 | ENSP00000274680 | ENSP00000282276 | phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins | methionyl-tRNA synthetase 2, mitochondrial | 0.948 |
FARS2 | NARS2 | ENSP00000274680 | ENSP00000281038 | phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | 0.859 |
FARS2 | RARS2 | ENSP00000274680 | ENSP00000358549 | phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins | arginyl-tRNA synthetase 2, mitochondrial | 0.915 |
FARS2 | YARS | ENSP00000274680 | ENSP00000362576 | phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) | 0.995 |
IARS2 | EPRS | ENSP00000303279 | ENSP00000355890 | isoleucyl-tRNA synthetase 2, mitochondrial | glutamyl-prolyl-tRNA synthetase | 0.895 |