FAM151B protein (Homo sapiens) - STRING network view

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FAM151B

family with sequence similarity 151, member B (276 aa)

Predicted Functional Partners:

ZCCHC9

0.723

SSBP2

0.534

RASGRF2

0.503

ZFYVE16

0.472

VCL

0.455

NRCAM

0.443

L1CAM

0.443

NFASC

0.443

CHL1

0.443

CKMT2

0.416

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHL1	FAM151B	ENSP00000256509	ENSP00000282226	cell adhesion molecule with homology to L1CAM (close homolog of L1); Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dep [...]	family with sequence similarity 151, member B	0.443
CKMT2	FAM151B	ENSP00000254035	ENSP00000282226	creatine kinase, mitochondrial 2 (sarcomeric); Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa	family with sequence similarity 151, member B	0.416
CKMT2	ZCCHC9	ENSP00000254035	ENSP00000254037	creatine kinase, mitochondrial 2 (sarcomeric); Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa	zinc finger, CCHC domain containing 9	0.474
CKMT2	ZFYVE16	ENSP00000254035	ENSP00000337159	creatine kinase, mitochondrial 2 (sarcomeric); Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa	zinc finger, FYVE domain containing 16; May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes	0.401
FAM151B	CHL1	ENSP00000282226	ENSP00000256509	family with sequence similarity 151, member B	cell adhesion molecule with homology to L1CAM (close homolog of L1); Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dep [...]	0.443
FAM151B	CKMT2	ENSP00000282226	ENSP00000254035	family with sequence similarity 151, member B	creatine kinase, mitochondrial 2 (sarcomeric); Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa	0.416
FAM151B	L1CAM	ENSP00000282226	ENSP00000359074	family with sequence similarity 151, member B	L1 cell adhesion molecule; Cell adhesion molecule with an important role in the development of the nervous system. Involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Binds to axonin on neurons	0.443
FAM151B	NFASC	ENSP00000282226	ENSP00000344786	family with sequence similarity 151, member B	neurofascin	0.443
FAM151B	NRCAM	ENSP00000282226	ENSP00000368314	family with sequence similarity 151, member B	neuronal cell adhesion molecule; Cell adhesion, ankyrin-binding protein involved in neuron-neuron adhesion. May play a role in the molecular assembly of the nodes of Ranvier (By similarity)	0.443
FAM151B	RASGRF2	ENSP00000282226	ENSP00000265080	family with sequence similarity 151, member B	Ras protein-specific guanine nucleotide-releasing factor 2; Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Functions in synaptic plasticity by contributing to the induction of long term potentiation	0.503
FAM151B	SSBP2	ENSP00000282226	ENSP00000322977	family with sequence similarity 151, member B	single-stranded DNA binding protein 2	0.534
FAM151B	VCL	ENSP00000282226	ENSP00000211998	family with sequence similarity 151, member B	vinculin; Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion	0.455
FAM151B	ZCCHC9	ENSP00000282226	ENSP00000254037	family with sequence similarity 151, member B	zinc finger, CCHC domain containing 9	0.723
FAM151B	ZFYVE16	ENSP00000282226	ENSP00000337159	family with sequence similarity 151, member B	zinc finger, FYVE domain containing 16; May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes	0.472
L1CAM	FAM151B	ENSP00000359074	ENSP00000282226	L1 cell adhesion molecule; Cell adhesion molecule with an important role in the development of the nervous system. Involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Binds to axonin on neurons	family with sequence similarity 151, member B	0.443
NFASC	FAM151B	ENSP00000344786	ENSP00000282226	neurofascin	family with sequence similarity 151, member B	0.443
NFASC	NRCAM	ENSP00000344786	ENSP00000368314	neurofascin	neuronal cell adhesion molecule; Cell adhesion, ankyrin-binding protein involved in neuron-neuron adhesion. May play a role in the molecular assembly of the nodes of Ranvier (By similarity)	0.958
NRCAM	FAM151B	ENSP00000368314	ENSP00000282226	neuronal cell adhesion molecule; Cell adhesion, ankyrin-binding protein involved in neuron-neuron adhesion. May play a role in the molecular assembly of the nodes of Ranvier (By similarity)	family with sequence similarity 151, member B	0.443
NRCAM	NFASC	ENSP00000368314	ENSP00000344786	neuronal cell adhesion molecule; Cell adhesion, ankyrin-binding protein involved in neuron-neuron adhesion. May play a role in the molecular assembly of the nodes of Ranvier (By similarity)	neurofascin	0.958
RASGRF2	FAM151B	ENSP00000265080	ENSP00000282226	Ras protein-specific guanine nucleotide-releasing factor 2; Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Functions in synaptic plasticity by contributing to the induction of long term potentiation	family with sequence similarity 151, member B	0.503

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