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STRINGSTRING
CAPSL CAPSL FAM216A FAM216A LYSMD2 LYSMD2 ACAD10 ACAD10 UGT3A2 UGT3A2 GHR GHR ACAD11 ACAD11 SLC35A2 SLC35A2 UBXN1 UBXN1
"UGT3A2" - UDP glycosyltransferase 3 family, polypeptide A2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
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colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
UGT3A2UDP glycosyltransferase 3 family, polypeptide A2; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity) (523 aa)    
Predicted Functional Partners:
ACAD11
acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA (780 aa)
            score_image   0.612
GHR
growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity) (638 aa)
            score_image   0.562
ACAD10
acyl-CoA dehydrogenase family, member 10; Acyl-CoA dehydrogenase only active with R- and S-2- methyl-C15-CoA (1090 aa)
            score_image   0.499
UBXN1
UBX domain protein 1; Ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. Specifically binds ’Lys-6’-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol (312 aa)
            score_image   0.440
SLC35A2
solute carrier family 35 (UDP-galactose transporter), member A2; Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function (396 aa)
            score_image   0.427
FAM216A
family with sequence similarity 216, member A (273 aa)
            score_image   0.418
LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2 (215 aa)
            score_image   0.412
CAPSL
calcyphosine-like (208 aa)
            score_image   0.404
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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