node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABAT | GADL1 | ENSP00000268251 | ENSP00000282538 | 4-aminobutyrate aminotransferase; Catalyzes the conversion of gamma-aminobutyrate and L- beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine | glutamate decarboxylase-like 1 | 0.651 |
AGXT2 | GADL1 | ENSP00000231420 | ENSP00000282538 | alanine--glyoxylate aminotransferase 2; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure | glutamate decarboxylase-like 1 | 0.668 |
AGXT2L1 | GADL1 | ENSP00000296486 | ENSP00000282538 | alanine-glyoxylate aminotransferase 2-like 1; Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde | glutamate decarboxylase-like 1 | 0.651 |
AGXT2L2 | GADL1 | ENSP00000310978 | ENSP00000282538 | alanine-glyoxylate aminotransferase 2-like 2; Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde | glutamate decarboxylase-like 1 | 0.659 |
CAD | GADL1 | ENSP00000264705 | ENSP00000282538 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | glutamate decarboxylase-like 1 | 0.855 |
CCDC73 | GADL1 | ENSP00000335325 | ENSP00000282538 | coiled-coil domain containing 73 | glutamate decarboxylase-like 1 | 0.560 |
GADL1 | ABAT | ENSP00000282538 | ENSP00000268251 | glutamate decarboxylase-like 1 | 4-aminobutyrate aminotransferase; Catalyzes the conversion of gamma-aminobutyrate and L- beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine | 0.651 |
GADL1 | AGXT2 | ENSP00000282538 | ENSP00000231420 | glutamate decarboxylase-like 1 | alanine--glyoxylate aminotransferase 2; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure | 0.668 |
GADL1 | AGXT2L1 | ENSP00000282538 | ENSP00000296486 | glutamate decarboxylase-like 1 | alanine-glyoxylate aminotransferase 2-like 1; Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde | 0.651 |
GADL1 | AGXT2L2 | ENSP00000282538 | ENSP00000310978 | glutamate decarboxylase-like 1 | alanine-glyoxylate aminotransferase 2-like 2; Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde | 0.659 |
GADL1 | CAD | ENSP00000282538 | ENSP00000264705 | glutamate decarboxylase-like 1 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | 0.855 |
GADL1 | CCDC73 | ENSP00000282538 | ENSP00000335325 | glutamate decarboxylase-like 1 | coiled-coil domain containing 73 | 0.560 |
GADL1 | LMX1A | ENSP00000282538 | ENSP00000294816 | glutamate decarboxylase-like 1 | LIM homeobox transcription factor 1, alpha; Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae (By similarity) | 0.736 |
GADL1 | LMX1B | ENSP00000282538 | ENSP00000347684 | glutamate decarboxylase-like 1 | LIM homeobox transcription factor 1, beta; Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels | 0.736 |
GADL1 | PABPC4L | ENSP00000282538 | ENSP00000462986 | glutamate decarboxylase-like 1 | poly(A) binding protein, cytoplasmic 4-like; May bind RNA (Potential) | 0.632 |
GADL1 | SLC25A16 | ENSP00000282538 | ENSP00000265870 | glutamate decarboxylase-like 1 | solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16; Required for the accumulation of coenzyme A in the mitochondrial matrix | 0.636 |
LMX1A | GADL1 | ENSP00000294816 | ENSP00000282538 | LIM homeobox transcription factor 1, alpha; Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae (By similarity) | glutamate decarboxylase-like 1 | 0.736 |
LMX1B | GADL1 | ENSP00000347684 | ENSP00000282538 | LIM homeobox transcription factor 1, beta; Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels | glutamate decarboxylase-like 1 | 0.736 |
PABPC4L | GADL1 | ENSP00000462986 | ENSP00000282538 | poly(A) binding protein, cytoplasmic 4-like; May bind RNA (Potential) | glutamate decarboxylase-like 1 | 0.632 |
SLC25A16 | GADL1 | ENSP00000265870 | ENSP00000282538 | solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16; Required for the accumulation of coenzyme A in the mitochondrial matrix | glutamate decarboxylase-like 1 | 0.636 |