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CAD CAD PABPC4L PABPC4L LMX1B LMX1B CCDC73 CCDC73 AGXT2L2 AGXT2L2 GADL1 GADL1 AGXT2L1 AGXT2L1 AGXT2 AGXT2 LMX1A LMX1A ABAT ABAT SLC25A16 SLC25A16
"GADL1" - glutamate decarboxylase-like 1 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small nodes:
protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
GADL1glutamate decarboxylase-like 1 (521 aa)    
Predicted Functional Partners:
CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) (2225 aa)
      score_image score_image   score_image   0.855
LMX1B
LIM homeobox transcription factor 1, beta; Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels (406 aa)
            score_image   0.736
LMX1A
LIM homeobox transcription factor 1, alpha; Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae (By similarity) (382 aa)
            score_image   0.736
AGXT2
alanine--glyoxylate aminotransferase 2; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (514 aa)
score_image score_image   score_image score_image   score_image   0.668
AGXT2L2
alanine-glyoxylate aminotransferase 2-like 2; Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde (450 aa)
score_image score_image   score_image score_image   score_image   0.659
AGXT2L1
alanine-glyoxylate aminotransferase 2-like 1; Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde (499 aa)
score_image score_image   score_image score_image   score_image   0.651
ABAT
4-aminobutyrate aminotransferase; Catalyzes the conversion of gamma-aminobutyrate and L- beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine (500 aa)
score_image     score_image score_image   score_image   0.651
SLC25A16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16; Required for the accumulation of coenzyme A in the mitochondrial matrix (332 aa)
            score_image   0.636
PABPC4L
poly(A) binding protein, cytoplasmic 4-like; May bind RNA (Potential) (428 aa)
            score_image   0.632
CCDC73
coiled-coil domain containing 73 (1079 aa)
            score_image   0.560
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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