node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C1orf114 | CCDC148 | ENSP00000356779 | ENSP00000283233 | chromosome 1 open reading frame 114 | coiled-coil domain containing 148 | 0.652 |
C1orf114 | CDH26 | ENSP00000356779 | ENSP00000339390 | chromosome 1 open reading frame 114 | cadherin 26; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | 0.523 |
CCDC148 | C1orf114 | ENSP00000283233 | ENSP00000356779 | coiled-coil domain containing 148 | chromosome 1 open reading frame 114 | 0.652 |
CCDC148 | CCDC40 | ENSP00000283233 | ENSP00000380679 | coiled-coil domain containing 148 | coiled-coil domain containing 40; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39 | 0.412 |
CCDC148 | CDH26 | ENSP00000283233 | ENSP00000339390 | coiled-coil domain containing 148 | cadherin 26; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | 0.672 |
CCDC148 | CLUAP1 | ENSP00000283233 | ENSP00000460850 | coiled-coil domain containing 148 | clusterin associated protein 1; Required for cilia biogenesis. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Key regulator of hedgehog signaling (By similarity) | 0.417 |
CCDC148 | GALNT13 | ENSP00000283233 | ENSP00000376570 | coiled-coil domain containing 148 | UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a much stronger activity than GALNT1 to transfer GalNAc to mucin peptides, such as Muc5Ac and Muc7. Able to glycosylate SDC3. May be responsible for the synthesis of Tn antigen in neuronal cells | 0.480 |
CCDC148 | LRRC49 | ENSP00000283233 | ENSP00000260382 | coiled-coil domain containing 148 | leucine rich repeat containing 49 | 0.693 |
CCDC148 | PPP1R32 | ENSP00000283233 | ENSP00000344140 | coiled-coil domain containing 148 | protein phosphatase 1, regulatory subunit 32 | 0.412 |
CCDC148 | RPAP2 | ENSP00000283233 | ENSP00000359368 | coiled-coil domain containing 148 | RNA polymerase II associated protein 2; Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated ’Ser-7’ of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of ’Ser-5’ of the CTD, thereby promoting transcription of snRNA genes | 0.509 |
CCDC148 | SAT1 | ENSP00000283233 | ENSP00000368572 | coiled-coil domain containing 148 | spermidine/spermine N1-acetyltransferase 1; Enzyme which catalyzes the acetylation of polyamines. Substrate specificity- norspermidine = spermidine >> spermine > N(1)-acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-acetylspermidine and N(8)-acetylspermidine | 0.673 |
CCDC148 | SLC47A2 | ENSP00000283233 | ENSP00000326671 | coiled-coil domain containing 148 | solute carrier family 47, member 2; Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes | 0.422 |
CCDC40 | CCDC148 | ENSP00000380679 | ENSP00000283233 | coiled-coil domain containing 40; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39 | coiled-coil domain containing 148 | 0.412 |
CCDC40 | LRRC49 | ENSP00000380679 | ENSP00000260382 | coiled-coil domain containing 40; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39 | leucine rich repeat containing 49 | 0.408 |
CDH26 | C1orf114 | ENSP00000339390 | ENSP00000356779 | cadherin 26; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | chromosome 1 open reading frame 114 | 0.523 |
CDH26 | CCDC148 | ENSP00000339390 | ENSP00000283233 | cadherin 26; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | coiled-coil domain containing 148 | 0.672 |
CDH26 | LRRC49 | ENSP00000339390 | ENSP00000260382 | cadherin 26; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | leucine rich repeat containing 49 | 0.613 |
CLUAP1 | CCDC148 | ENSP00000460850 | ENSP00000283233 | clusterin associated protein 1; Required for cilia biogenesis. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Key regulator of hedgehog signaling (By similarity) | coiled-coil domain containing 148 | 0.417 |
CLUAP1 | LRRC49 | ENSP00000460850 | ENSP00000260382 | clusterin associated protein 1; Required for cilia biogenesis. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Key regulator of hedgehog signaling (By similarity) | leucine rich repeat containing 49 | 0.412 |
GALNT13 | CCDC148 | ENSP00000376570 | ENSP00000283233 | UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a much stronger activity than GALNT1 to transfer GalNAc to mucin peptides, such as Muc5Ac and Muc7. Able to glycosylate SDC3. May be responsible for the synthesis of Tn antigen in neuronal cells | coiled-coil domain containing 148 | 0.480 |