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GDI1 GDI1 GDI2 GDI2 ADAMTS9 ADAMTS9 CAMK1D CAMK1D THADA THADA JAZF1 JAZF1 UHRF1BP1 UHRF1BP1 CDC123 CDC123 PPARG PPARG NAMPT NAMPT NR2C2 NR2C2
"JAZF1" - JAZF zinc finger 1 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small nodes:
protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
JAZF1JAZF zinc finger 1; Potential transcription factor (243 aa)    
Predicted Functional Partners:
NR2C2
nuclear receptor subfamily 2, group C, member 2; Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear recptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elemen [...] (615 aa)
        score_image   score_image   0.940
GDI1
GDP dissociation inhibitor 1; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (447 aa)
        score_image   score_image   0.833
GDI2
GDP dissociation inhibitor 2; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (445 aa)
        score_image   score_image   0.833
UHRF1BP1
UHRF1 binding protein 1; May act as a negative regulator of cell growth (1440 aa)
            score_image   0.831
CDC123
cell division cycle 123 homolog (S. cerevisiae); Required for S phase entry of the cell cycle (By similarity) (336 aa)
            score_image   0.810
NAMPT
nicotinamide phosphoribosyltransferase; Catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway (By similarity) (491 aa)
            score_image   0.801
CAMK1D
calcium/calmodulin-dependent protein kinase ID; Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine- induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleu [...] (385 aa)
            score_image   0.771
THADA
thyroid adenoma associated (1953 aa)
            score_image   0.770
PPARG
peroxisome proliferator-activated receptor gamma (505 aa)
        score_image   score_image   0.766
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9; Cleaves the large aggregating proteoglycans, aggrecan and versican (1935 aa)
            score_image   0.756
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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