| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BANK1 | BLK | ENSP00000320509 | ENSP00000259089 | B-cell scaffold protein with ankyrin repeats 1; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2 | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | 0.765 |
| BANK1 | FAM167A | ENSP00000320509 | ENSP00000284486 | B-cell scaffold protein with ankyrin repeats 1; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2 | family with sequence similarity 167, member A | 0.725 |
| BANK1 | IRF5 | ENSP00000320509 | ENSP00000349770 | B-cell scaffold protein with ankyrin repeats 1; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2 | interferon regulatory factor 5 | 0.631 |
| BANK1 | PHRF1 | ENSP00000320509 | ENSP00000410626 | B-cell scaffold protein with ankyrin repeats 1; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2 | PHD and ring finger domains 1 | 0.700 |
| BANK1 | PXK | ENSP00000320509 | ENSP00000348472 | B-cell scaffold protein with ankyrin repeats 1; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2 | PX domain containing serine/threonine kinase | 0.658 |
| BANK1 | STAT4 | ENSP00000320509 | ENSP00000351255 | B-cell scaffold protein with ankyrin repeats 1; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2 | signal transducer and activator of transcription 4; Carries out a dual function- signal transduction and activation of transcription. Involved in IL12 signaling | 0.647 |
| BANK1 | TRPM6 | ENSP00000320509 | ENSP00000354006 | B-cell scaffold protein with ankyrin repeats 1; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2 | transient receptor potential cation channel, subfamily M, member 6; Essential ion channel and serine/threonine-protein kinase. Crucial for magnesium homeostasis. Has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Isoforms of the type M6-kinase lack the ion channel region | 0.414 |
| BANK1 | UHRF1BP1 | ENSP00000320509 | ENSP00000192788 | B-cell scaffold protein with ankyrin repeats 1; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2 | UHRF1 binding protein 1; May act as a negative regulator of cell growth | 0.508 |
| BLK | BANK1 | ENSP00000259089 | ENSP00000320509 | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | B-cell scaffold protein with ankyrin repeats 1; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2 | 0.765 |
| BLK | FAM167A | ENSP00000259089 | ENSP00000284486 | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | family with sequence similarity 167, member A | 0.873 |
| BLK | IRF5 | ENSP00000259089 | ENSP00000349770 | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | interferon regulatory factor 5 | 0.700 |
| BLK | MTMR9 | ENSP00000259089 | ENSP00000221086 | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | myotubularin related protein 9; Probable pseudophosphatase. Contains a Gly residue instead of a conserved Cys residue in the dsPTPase catalytic loop which renders it catalytically inactive as a phosphatase (Potential) | 0.515 |
| BLK | PHRF1 | ENSP00000259089 | ENSP00000410626 | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | PHD and ring finger domains 1 | 0.723 |
| BLK | PXK | ENSP00000259089 | ENSP00000348472 | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | PX domain containing serine/threonine kinase | 0.742 |
| BLK | STAT4 | ENSP00000259089 | ENSP00000351255 | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | signal transducer and activator of transcription 4; Carries out a dual function- signal transduction and activation of transcription. Involved in IL12 signaling | 0.893 |
| BLK | TRPM6 | ENSP00000259089 | ENSP00000354006 | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | transient receptor potential cation channel, subfamily M, member 6; Essential ion channel and serine/threonine-protein kinase. Crucial for magnesium homeostasis. Has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Isoforms of the type M6-kinase lack the ion channel region | 0.566 |
| BLK | UHRF1BP1 | ENSP00000259089 | ENSP00000192788 | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | UHRF1 binding protein 1; May act as a negative regulator of cell growth | 0.726 |
| FAM167A | BANK1 | ENSP00000284486 | ENSP00000320509 | family with sequence similarity 167, member A | B-cell scaffold protein with ankyrin repeats 1; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2 | 0.725 |
| FAM167A | BLK | ENSP00000284486 | ENSP00000259089 | family with sequence similarity 167, member A | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | 0.873 |
| FAM167A | IRF5 | ENSP00000284486 | ENSP00000349770 | family with sequence similarity 167, member A | interferon regulatory factor 5 | 0.660 |
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