node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP5B | ATP6V1A | ENSP00000262030 | ENSP00000273398 | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is couple [...] | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells | 0.926 |
ATP5B | OLA1 | ENSP00000262030 | ENSP00000284719 | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is couple [...] | Obg-like ATPase 1 | 0.892 |
ATP5B | TOP2A | ENSP00000262030 | ENSP00000411532 | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is couple [...] | topoisomerase (DNA) II alpha 170kDa | 0.579 |
ATP5B | TOP2B | ENSP00000262030 | ENSP00000396704 | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is couple [...] | topoisomerase (DNA) II beta 180kDa; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Indirectly involved in vitamin D- coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR- mediated transrepression of the CYP27B1 gene | 0.587 |
ATP5B | UBC | ENSP00000262030 | ENSP00000344818 | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is couple [...] | ubiquitin C | 0.970 |
ATP6V1A | ATP5B | ENSP00000273398 | ENSP00000262030 | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is couple [...] | 0.926 |
ATP6V1A | OLA1 | ENSP00000273398 | ENSP00000284719 | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells | Obg-like ATPase 1 | 0.868 |
ATP6V1A | UBC | ENSP00000273398 | ENSP00000344818 | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells | ubiquitin C | 0.978 |
EEF1G | ENSG00000232856 | ENSP00000331901 | ENSP00000403936 | eukaryotic translation elongation factor 1 gamma; Probably plays a role in anchoring the complex to other cellular components | hsa-mir-3654 | 0.580 |
EEF1G | GCN1L1 | ENSP00000331901 | ENSP00000300648 | eukaryotic translation elongation factor 1 gamma; Probably plays a role in anchoring the complex to other cellular components | GCN1 general control of amino-acid synthesis 1-like 1 (yeast) | 0.772 |
EEF1G | HSPA4 | ENSP00000331901 | ENSP00000302961 | eukaryotic translation elongation factor 1 gamma; Probably plays a role in anchoring the complex to other cellular components | heat shock 70kDa protein 4 | 0.444 |
EEF1G | OLA1 | ENSP00000331901 | ENSP00000284719 | eukaryotic translation elongation factor 1 gamma; Probably plays a role in anchoring the complex to other cellular components | Obg-like ATPase 1 | 0.861 |
EEF1G | PSMC5 | ENSP00000331901 | ENSP00000310572 | eukaryotic translation elongation factor 1 gamma; Probably plays a role in anchoring the complex to other cellular components | proteasome (prosome, macropain) 26S subunit, ATPase, 5; The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex | 0.837 |
EEF1G | UBC | ENSP00000331901 | ENSP00000344818 | eukaryotic translation elongation factor 1 gamma; Probably plays a role in anchoring the complex to other cellular components | ubiquitin C | 0.998 |
ENSG00000232856 | EEF1G | ENSP00000403936 | ENSP00000331901 | hsa-mir-3654 | eukaryotic translation elongation factor 1 gamma; Probably plays a role in anchoring the complex to other cellular components | 0.580 |
ENSG00000232856 | GCN1L1 | ENSP00000403936 | ENSP00000300648 | hsa-mir-3654 | GCN1 general control of amino-acid synthesis 1-like 1 (yeast) | 0.759 |
ENSG00000232856 | HSPA4 | ENSP00000403936 | ENSP00000302961 | hsa-mir-3654 | heat shock 70kDa protein 4 | 0.426 |
ENSG00000232856 | OLA1 | ENSP00000403936 | ENSP00000284719 | hsa-mir-3654 | Obg-like ATPase 1 | 0.861 |
ENSG00000232856 | PSMC5 | ENSP00000403936 | ENSP00000310572 | hsa-mir-3654 | proteasome (prosome, macropain) 26S subunit, ATPase, 5; The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex | 0.836 |
ENSG00000232856 | UBC | ENSP00000403936 | ENSP00000344818 | hsa-mir-3654 | ubiquitin C | 0.722 |