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STRINGSTRING
ATP5B ATP5B TOP2B TOP2B ATP6V1A ATP6V1A TOP2A TOP2A OLA1 OLA1 HSPA4 HSPA4 UBC UBC EEF1G EEF1G GCN1L1 GCN1L1 ENSG00000232856 ENSG00000232856 PSMC5 PSMC5
"OLA1" - Obg-like ATPase 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
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colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
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[Homology]
Score
OLA1Obg-like ATPase 1 (396 aa)    
Predicted Functional Partners:
UBC
ubiquitin C (685 aa)
      score_image score_image       0.933
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is couple [...] (529 aa)
      score_image score_image       0.892
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (617 aa)
      score_image score_image       0.868
ENSG00000232856
hsa-mir-3654 (206 aa)
      score_image score_image       0.861
EEF1G
eukaryotic translation elongation factor 1 gamma; Probably plays a role in anchoring the complex to other cellular components (437 aa)
      score_image score_image       0.861
GCN1L1
GCN1 general control of amino-acid synthesis 1-like 1 (yeast) (2671 aa)
      score_image score_image       0.812
TOP2A
topoisomerase (DNA) II alpha 170kDa (1531 aa)
score_image     score_image score_image   score_image   0.766
TOP2B
topoisomerase (DNA) II beta 180kDa; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Indirectly involved in vitamin D- coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR- mediated transrepression of the CYP27B1 gene (1621 aa)
score_image     score_image score_image   score_image   0.766
PSMC5
proteasome (prosome, macropain) 26S subunit, ATPase, 5; The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (406 aa)
      score_image score_image       0.733
HSPA4
heat shock 70kDa protein 4 (840 aa)
      score_image score_image   score_image   0.723
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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