Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | MRPS17 | mitochondrial ribosomal protein S17 (130 aa) | ||||||||||||
Predicted Functional Partners:
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 | UBC | ubiquitin C (685 aa) |
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0.721 | ||||||||||
 | MRPS14 | mitochondrial ribosomal protein S14 (128 aa) |
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0.692 | ||||||||
 | MRPL9 | mitochondrial ribosomal protein L9 (267 aa) |
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0.604 | |||||||||
 | RPL3 | ribosomal protein L3; The L3 protein is a component of the large subunit of cytoplasmic ribosomes (403 aa) |
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0.598 | ||||||||||
 | MRPS2 | mitochondrial ribosomal protein S2 (296 aa) |
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0.596 | ||||||||
 | ENSG00000262660 | Mitochondrial dicarboxylate carrier; Uncharacterized protein; cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier (442 aa) |
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0.587 | |||||||||
 | MRPL12 | mitochondrial ribosomal protein L12 (198 aa) |
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0.570 | |||||||||
 | MRPS24 | mitochondrial ribosomal protein S24 (167 aa) |
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0.560 | ||||||||
 | MRPS15 | mitochondrial ribosomal protein S15 (257 aa) |
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0.558 | ||||||||
 | MRPL32 | mitochondrial ribosomal protein L32 (188 aa) |
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0.547 | |||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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