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STRINGSTRING
FAM60A FAM60A LINC00493 LINC00493 ZNF217 ZNF217 HDAC1 HDAC1 HDAC2 HDAC2 C16orf87 C16orf87 IKZF2 IKZF2 ARID5B ARID5B GEMIN4 GEMIN4 BBX BBX ZNF215 ZNF215
"C16orf87" - chromosome 16 open reading frame 87 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
C16orf87chromosome 16 open reading frame 87 (154 aa)    
Predicted Functional Partners:
ARID5B
AT rich interactive domain 5B (MRF1-like) (1188 aa)
            score_image   0.651
BBX
bobby sox homolog (Drosophila); Transcription factor that is necessary for cell cycle progression from G1 to S phase (941 aa)
            score_image   0.646
HDAC2
histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed o [...] (488 aa)
        score_image       0.615
HDAC1
histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST- mediated transcription in resting neurons. Upon calcium s [...] (482 aa)
        score_image       0.615
FAM60A
family with sequence similarity 60, member A; Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathway (221 aa)
            score_image   0.582
ZNF217
zinc finger protein 217; Binds to the promoters of target genes and functions as repressor. Promotes cell proliferation and antagonizes cell death. Promotes phosphorylation of AKT1 at ’Ser-473’ (1048 aa)
            score_image   0.533
ZNF215
zinc finger protein 215; May be involved in transcriptional regulation (517 aa)
            score_image   0.514
GEMIN4
gem (nuclear organelle) associated protein 4; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus (1058 aa)
            score_image   0.478
IKZF2
IKAROS family zinc finger 2 (Helios); Associates with Ikaros at centromeric heterochromatin (526 aa)
            score_image   0.471
LINC00493
long intergenic non-protein coding RNA 493 (95 aa)
      score_image     score_image   0.427
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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