ALS2CR12 protein (Homo sapiens) - STRING network view

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Score

ALS2CR12

amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12 (445 aa)

Predicted Functional Partners:

SULT2B1

0.879

TRAK2

0.457

ALS2

0.450

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALS2	ALS2CR12	ENSP00000264276	ENSP00000286190	amyotrophic lateral sclerosis 2 (juvenile); May act as a GTPase regulator. Controls survival and growth of spinal motoneurons (By similarity)	amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12	0.450
ALS2	TRAK2	ENSP00000264276	ENSP00000328875	amyotrophic lateral sclerosis 2 (juvenile); May act as a GTPase regulator. Controls survival and growth of spinal motoneurons (By similarity)	trafficking protein, kinesin binding 2; May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR (By similarity)	0.683
ALS2CR12	ALS2	ENSP00000286190	ENSP00000264276	amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12	amyotrophic lateral sclerosis 2 (juvenile); May act as a GTPase regulator. Controls survival and growth of spinal motoneurons (By similarity)	0.450
ALS2CR12	SULT2B1	ENSP00000286190	ENSP00000201586	amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12	sulfotransferase family, cytosolic, 2B, member 1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol	0.879
ALS2CR12	TRAK2	ENSP00000286190	ENSP00000328875	amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12	trafficking protein, kinesin binding 2; May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR (By similarity)	0.457
SULT2B1	ALS2CR12	ENSP00000201586	ENSP00000286190	sulfotransferase family, cytosolic, 2B, member 1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol	amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12	0.879
TRAK2	ALS2	ENSP00000328875	ENSP00000264276	trafficking protein, kinesin binding 2; May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR (By similarity)	amyotrophic lateral sclerosis 2 (juvenile); May act as a GTPase regulator. Controls survival and growth of spinal motoneurons (By similarity)	0.683
TRAK2	ALS2CR12	ENSP00000328875	ENSP00000286190	trafficking protein, kinesin binding 2; May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR (By similarity)	amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12	0.457

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