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STRINGSTRING
SCMH1 SCMH1 PRKG2 PRKG2 ANAPC13 ANAPC13 ADAMTSL3 ADAMTSL3 TOP1 TOP1 DLEU7 DLEU7 SLC2A5 SLC2A5
"ADAMTSL3" - ADAMTS-like 3 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAMTSL3ADAMTS-like 3 (1691 aa)    
Predicted Functional Partners:
PRKG2
protein kinase, cGMP-dependent, type II (762 aa)
            score_image   0.562
DLEU7
deleted in lymphocytic leukemia, 7 (160 aa)
            score_image   0.501
ANAPC13
anaphase promoting complex subunit 13; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins- it mainly mediates the formation of ’Lys-11’-linked polyubiquitin chains and, to a lower extent, the formation of ’Lys-48’- and ’Lys-63’-linked polyubiquitin chains (74 aa)
            score_image   0.434
TOP1
topoisomerase (DNA) I (765 aa)
            score_image   0.429
SCMH1
sex comb on midleg homolog 1 (Drosophila); Associates with Polycomb group (PcG) multiprotein complexes; the complex class is required to maintain the transcriptionally repressive state of some genes (By similarity) (660 aa)
            score_image   0.418
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5; Cytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter (501 aa)
            score_image   0.410
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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