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STRINGSTRING
ACOX1 ACOX1 ENSG00000260170 ENSG00000260170 ACOX3 ACOX3 UBC UBC ACACA ACACA DHRS1 DHRS1 ACACB ACACB DHRS2 DHRS2 SDPR SDPR RDH10 RDH10 ACOX2 ACOX2
"DHRS1" - dehydrogenase/reductase (SDR family) member 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
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colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
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Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
DHRS1dehydrogenase/reductase (SDR family) member 1 (313 aa)    
Predicted Functional Partners:
SDPR
serum deprivation response; May play a role in targeting PRKCA to caveolae (By similarity) (425 aa)
            score_image   0.866
UBC
ubiquitin C (685 aa)
        score_image       0.864
DHRS2
dehydrogenase/reductase (SDR family) member 2; Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2- propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. May inhibit cell replication (300 aa)
    score_image score_image     score_image   0.625
ACACA
acetyl-CoA carboxylase alpha (2383 aa)
score_image           score_image   0.581
ACACB
acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase (2458 aa)
score_image           score_image   0.581
RDH10
retinol dehydrogenase 10 (all-trans); Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol (341 aa)
    score_image       score_image   0.558
ENSG00000260170
Uncharacterized protein (289 aa)
            score_image   0.518
ACOX3
acyl-CoA oxidase 3, pristanoyl; Oxidizes the CoA-esters of 2-methyl-branched fatty acids (By similarity) (700 aa)
      score_image     score_image   0.487
ACOX2
acyl-CoA oxidase 2, branched chain; Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids (681 aa)
      score_image     score_image   0.487
ACOX1
acyl-CoA oxidase 1, palmitoyl (660 aa)
      score_image     score_image   0.487
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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