node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARMC4 | C19orf52 | ENSP00000306410 | ENSP00000270502 | armadillo repeat containing 4 | chromosome 19 open reading frame 52 | 0.472 |
ARMC4 | CCDC114 | ENSP00000306410 | ENSP00000318429 | armadillo repeat containing 4 | coiled-coil domain containing 114; Probable component of the outer dynein arm complex required along the entire axoneme for tethering of outer dynein arms (Probable) | 0.511 |
ARMC4 | CCDC164 | ENSP00000306410 | ENSP00000288710 | armadillo repeat containing 4 | coiled-coil domain containing 164; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Required for the assembly and regulation of specific classes of inner dynein arm motors. May also function to restrict dynein-driven microtubule sliding, thus aiding in the generation of ciliary bending | 0.721 |
ARMC4 | CCDC39 | ENSP00000306410 | ENSP00000405708 | armadillo repeat containing 4 | coiled-coil domain containing 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly | 0.689 |
ARMC4 | CCDC40 | ENSP00000306410 | ENSP00000380679 | armadillo repeat containing 4 | coiled-coil domain containing 40; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39 | 0.670 |
ARMC4 | CCDC65 | ENSP00000306410 | ENSP00000312706 | armadillo repeat containing 4 | coiled-coil domain containing 65 | 0.708 |
ARMC4 | DNAAF2 | ENSP00000306410 | ENSP00000298292 | armadillo repeat containing 4 | dynein, axonemal, assembly factor 2; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment | 0.586 |
ARMC4 | DNAAF3 | ENSP00000306410 | ENSP00000375599 | armadillo repeat containing 4 | dynein, axonemal, assembly factor 3; Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia | 0.693 |
ARMC4 | HEATR2 | ENSP00000306410 | ENSP00000297440 | armadillo repeat containing 4 | HEAT repeat containing 2 | 0.674 |
ARMC4 | RSPH4A | ENSP00000306410 | ENSP00000229554 | armadillo repeat containing 4 | radial spoke head 4 homolog A (Chlamydomonas); Probable component of the axonemal radial spoke head. Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They consist of a thin stalk which is attached to a subfiber of the outer doublet microtubule, and a bulbous head which is attached to the stalk and appears to interact with the projections from the central pair of microtubules | 0.438 |
C19orf52 | ARMC4 | ENSP00000270502 | ENSP00000306410 | chromosome 19 open reading frame 52 | armadillo repeat containing 4 | 0.472 |
C19orf52 | CCDC114 | ENSP00000270502 | ENSP00000318429 | chromosome 19 open reading frame 52 | coiled-coil domain containing 114; Probable component of the outer dynein arm complex required along the entire axoneme for tethering of outer dynein arms (Probable) | 0.660 |
C19orf52 | CCDC164 | ENSP00000270502 | ENSP00000288710 | chromosome 19 open reading frame 52 | coiled-coil domain containing 164; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Required for the assembly and regulation of specific classes of inner dynein arm motors. May also function to restrict dynein-driven microtubule sliding, thus aiding in the generation of ciliary bending | 0.700 |
C19orf52 | CCDC39 | ENSP00000270502 | ENSP00000405708 | chromosome 19 open reading frame 52 | coiled-coil domain containing 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly | 0.564 |
C19orf52 | CCDC40 | ENSP00000270502 | ENSP00000380679 | chromosome 19 open reading frame 52 | coiled-coil domain containing 40; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39 | 0.583 |
C19orf52 | CCDC65 | ENSP00000270502 | ENSP00000312706 | chromosome 19 open reading frame 52 | coiled-coil domain containing 65 | 0.648 |
C19orf52 | DNAAF2 | ENSP00000270502 | ENSP00000298292 | chromosome 19 open reading frame 52 | dynein, axonemal, assembly factor 2; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment | 0.439 |
C19orf52 | DNAAF3 | ENSP00000270502 | ENSP00000375599 | chromosome 19 open reading frame 52 | dynein, axonemal, assembly factor 3; Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia | 0.583 |
C19orf52 | HEATR2 | ENSP00000270502 | ENSP00000297440 | chromosome 19 open reading frame 52 | HEAT repeat containing 2 | 0.510 |
C19orf52 | RSPH4A | ENSP00000270502 | ENSP00000229554 | chromosome 19 open reading frame 52 | radial spoke head 4 homolog A (Chlamydomonas); Probable component of the axonemal radial spoke head. Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They consist of a thin stalk which is attached to a subfiber of the outer doublet microtubule, and a bulbous head which is attached to the stalk and appears to interact with the projections from the central pair of microtubules | 0.570 |